Non-opioid Pain Patch Market: Product Development is Key Focus for Market Leaders

Global Non-opioid Pain Patch Market: Need for Non-addictive Chronic Pain Treatment to Foster Growth

Global Non-opioid Pain Patch Market: Need for Non-addictive Chronic Pain Treatment to Foster Growth

Researchers have prioritized the search for non-opioid drugs with escalating rates of opioid addiction. For years, physicians had been providing an aggressive treatment for chronic treatment resulting in narcotic-addiction among patients. However, the healthcare industry is no longer marrying the concept of pain relief with narcotic analgesics. Medical pain-management as a whole is drifting away from addictive procedures or treatments towards evidence-based treatments using non-opioid analgesics.

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The sharp rise in the number of overdose deaths only echoes the magnitude of the crisis caused by the opioid epidemic. According to the World Health Organization, 27 Mn people suffered from opioid disorders in 2016. Overdose deaths accounted for around a third and a half of all the drug-related deaths.

The rising popularity of non-opioids as the “analgesics of the future” and efforts focused on tackling the crisis of “opioid epidemic” calls for a need to conduct an in-depth analysis of the non-opioid pain patch market. In its latest offering, Transparency Market Research talks about how the changes in healthcare trends and consumer demographics have impacted the market’s evolution.non opioid pain patch market

A Walk through the Evolutionary Timeline

As the consumers realized the ill-effects of opioid treatment, companies manufacturing and marketing these drugs faced public backlash. This acted as a stepping stone for the development of new non-opioid treatments which have redefined the non-opioid treatment market’s growth. In a bid to promote the use of non-opioid analgesics, the U.S. Food and Drug Administration (FDA) launched a campaign called the “innovation challenge”. It was aimed at the development of medical devices that could combat opioid use disorder.

The non-opioid pain match treatment market has come a long way from the development of the first patch product for PHN treatment in 2013 to the launch of OTC water-free lidocaine patch in March 2016. Furthermore, in February 2018, Tremeau Pharmaceuticals, Inc., closed the equity raise of $5.2 Mn to fund non-opioid treatments for rare diseases.

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With the escalating new developments, the global non-opioid pain patch market is poised to rise from its initial valuation of US$ 3,750 Mn in 2015 to reach US$ 4,983.3 Mn in 2024. However, the high popularity of oral pain relief drugs due to their ability to mitigate pain in a short duration may act a stumbling block in the non-opioid pain patch market.

Trends Causing a Stir in the Non-opioid Pain Patch Market

Rising Popularity of Transdermal Drug Delivery

Transdermal delivery despite being an unexplored aspect of drug delivery is gradually entering the league of blockbuster drugs. Capitalizing on this riveting trend, non-opioid drug manufacturers are developing transdermal non-opioid painkiller patches. Moreover, the Food and Drug Administration is keen on approving transdermal drugs because of their efficacy in reducing postoperative pain. For instance, in March 2018, the FDA approved the non-opioid painkiller patch developed by Sorrento. Market players are not only launching new non-opioids but relaunching high-selling NSAIDs as into transdermal drug delivery systems.

Replacement of Existing Pain Patches with Next Gen Patches

In a bid to enhance the efficiency of the pain patch treatment, leading players are concentrating their efforts on upgrading the existing pain patches or replacing them with next-generation pain patches. This trend of introducing the existing drug with a better design has helped manufacturers garner considerable attention from the physicians and the patients. One such example of upgradation of pain patches is the study conducted by SCILEX Pharmaceuticals Inc., for the development of ZTlido, an anhydrous patch created using the patented technology. The development of such trailblazing products has amplified the adoption of non-opioid pain patches for the treatment of chronic pain.

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Key Winning Imperatives

Development of Personalized Non-opioid Pain Patches

Personalized medicines have taken the medical industry by a storm with soaring number of drug manufacturers tailoring the medicines as per the patient’s needs. Banking on the rising demand for “tailored medicine”, manufacturers are relying on patient genotyping to develop personalized pain patches for the patients. Following the same trends, Assurex Health, Inc. is working on introducing a genomics test to check the suitability of pain patches. This move is also aimed at developing solution for chronic pain with considerably low side effects. This incorporation of pharmacogenomics in the non-opioid pain patch unlocks a major growth opportunity for the market players.

Building Alliances with Leading Hospitals

According to TMR’s study, consumers are most likely to buy non-opioid drugs from hospital pharmacies, making it the most preferred distribution channel for the manufacturers. Hospital pharmacies accounted for 48.3% of the non-opioid pain patch market’s share in 2016. As a result, manufacturers are building strong alliances with the leading hospitals to gain access to their customer base.

Players are also gradually moving towards online sales channels due to the improvements in the electronic payment technology. Consumer interest is gradually shifting towards online pharmacies due to the extensive range of medications available online and transparency offered in terms of prices.

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A Walk through the Competition Landscape

Market players in the non-opioid pain patch market share a moderate rivalry as the market is still in its nascent stage. Although the number of market players is less, they have remarkably high global reach due to strong brand identities. The top three players in the market including Hisamitsu

Pharmaceutical Co., Inc., Acorda Therapeutics, Inc., and Endo International plc account for nearly 40% of the global market share.

These companies are relying on mergers and acquisitions, co-promotion agreements, and developing novel treatments to sustain their position in the market. Below are a few recent strategies deployed by the leading market players:

  • Acorda Therapeutics has two phase 3 and one phase 2 drug candidates for Parkinson’s disease as of December 2016.
  • In February 2015, Endo International plc acquired Litha Healthcare Group in order develop advanced products using its expertise in specialty medicines.
  • In December 2016, Hisamitsu Pharmaceutical Co., Inc. filed an application for a transdermal drug for the treatment of allergic rhinitis in Japan.

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Mushrooming companies in regional markets are focusing on expanding their geographical reach through collaborations with leading pharmaceutical companies. Leading market players are supporting this move as it helps them gain access to local markets. However, it is hard to ignore the fact that this substantially increases the threat of new entrants and gives them a significant platform to proliferate the global market.

Asia Pacific hosts the highest number of regional players due to high prevalence of chronic pain and the history of opioid addiction. Some of the regional players in Asia Pacific include TEH SENG PharmaceuticalMfg. Co., Ltd., Teikoku Seiyaku Co., Ltd., and Hisamitsu Pharmaceutical Co., Inc.

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