MethylGene Inc. (TSX:MYG), will hold its Annual General Meeting of Shareholders on Thursday April 20th, 2006 at 10:00 a.m. (EDT) at Fairmont The Queen Elizabeth Hotel, 900 Rene-Levesque Blvd. West, Montreal, Quebec. For those who are unable to attend in person, the presentation given during the meeting will be available by webcast on the Company's website at www.methylgene.com.