While the prevalence of alcohol use disorders (AUDs) in the United States during the 1980s was roughly five times more common among men than women, the gap between the genders has narrowed: AUDs are now only twice as prevalent in men than in women. Treatment for alcohol dependence (AD) utilizes multiple therapeutic modalities, including pharmacotherapy. This study found that women respond to naltrexone treatment for AD similarly to men. Results will be published in the October 2010 issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View.