The report highlights trends prevailing in the market, and the factors driving and hindering the market growth.
According to our new research study on “DPCR and qPCR in Healthcare Market Forecast to 2027 – COVID-19 Impact and Global Analysis – by Component, Application, and End User,” the market is expected to reach US$ 6,371.6 million by 2025 from US$ 3,255.5 million in 2017; it is estimated to grow at a CAGR of 9.1% from 2018 to 2025. The report highlights trends prevailing in the market, and the factors driving and hindering the market growth. The growth of the dPCR and qPCRin healthcare market is attributed to the Increasing Incidence of Genetic Diseases, Increase in Investments & Funds for Gene Synthesis, Technological Advancements in PCR Technologies are key drivers for the growth of the market. However, factors such as High Costs of PCR Systems and Technical Limitations Associated with qPCR are likely to restrain the market growth to a certain extent.
dPCR and qPCR are PCR technology which have evolved over the years from thermostable polymerases, development of automated thermocyclers to latest digital PCR (d-PCR) methodologies. However, the basic principle of denature, anneal, extend remains the same. qPCR has spawned the second generation that allows analysis and diagnosis with reduced risk of contamination and is considered as ‘gold standard’. dPCR amplifies the target DNA molecule and quantifies directly without external calibrator. This has been used extensively for studying variations in gene sequences. With these numerous advantages the market is expected to witness rapid growth. The growth of the dPCR and qPCR in healthcare market is attributed to the Increasing Incidence of Genetic Diseases, Increase in Investments & Funds for Gene Synthesis, Technological Advancements in PCR Technologies are key drivers for the growth of the market. However, factors such as High Costs of PCR Systems and Technical Limitations Associated with qPCR are likely to restrain the market growth to a certain extent.
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dPCR and qPCR Market Competitive Landscape and Key Development
F. Hoffmann-La Roche Ltd, Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, Inc., Qiagen N.V., Takara Bio, Inc., Agilent Technologies, Inc., Biomérieux S.A., Fluidigm Corporation, Danaher Corporation, and ABBott Laboratories. are among the leading companies operating in the dPCR and qPCRin healthcare market.
The dPCR and qPCRin healthcare market is expected to witness substantial growth post-pandemic. The COVID-19 has affected economies and industries in various countries due to lockdowns, travel bans, and business shutdowns. The COVID-19 crisis has overburdened public health systems in many countries and highlighted the strong need for sustainable investment in health systems. As the COVID-19 pandemic progresses, the healthcare industry is expected to see a drop in growth. The life sciences segment thrives due to increased demand for invitro diagnostic products and rising research and development activities worldwide. However, the medical technologies and imaging segment is witnessing drop in sales due to a smaller number of surgeries being carried out and delayed or prolonged equipment procurement. Additionally, virtual consultations by healthcare professionals are expected to become the mainstream care delivery model post-pandemic. With telehealth transforming care delivery, digital health will continue to thrive in coming years. In addition, disrupted clinical trials and the subsequent delay in drug launches is also expected to pave the way for entirely virtual trials in the future. New technologies such as mRNA is expected to emerge and shift the pharmaceutical industry and market is also expected to witness more vertical integration and joint ventures in coming years.
Growing Applications of DPCR and qPCR in Healthcare to Drive DPCR and qPCR in Healthcare Market Growth
Genes are considered to be the building blocks of heredity. The genes are passed from a parent to a child, as well as they hold the DNA that is usually considered to instruct and guide protein synthesis. Mutation, on the other hand refers to a sudden change in a single or multiple genes. The mutation can result in dysfunction of the gene resulting in a medical condition called genetic disorder. According to the National organizations information on genetic conditions or birth defects, though individual genetic disorders are rare, collectively they comprise over 15,500 recognized genetic disorders.
Moreover, according to the Genetic Disorders UK, it is estimated that one in 25 children is affected by a genetic disorder and therefore 30,000 babies and children are newly diagnosed in the UK each year. According to the Genetic Home References, about 1 in 200,000 people in the United States are born with syndrome each year. An estimated 15,000 infants with syndrome B were born last year worldwide. Moreover, approximately 1 percent of people in the United States develop disorder D during their lifetimes. The lifetime risk of developing disorder D is 1 in 100. The adoption of digital PCR is improving as the pathologists are trying to track the use of this technology to target various specific DNA sequences as well as to diagnose and design various clinical tests. Digital PCR can target specific DNA sequences in just one molecule of DNA. This new tool allows researchers to isolate rare genetic mutations too difficult to segregate with realtime PCR. Thus, the increasing incidence of genetic diseases in which dPCR and qPCR techniques can be used for diagnosis and treatment options are expected to support the growth of the market over the forecast years.
Gene synthesis is mostly accepted tool in fields of recombinant DNA technology, which includes recombinant protein production and PCR technology for amplification as well as quantification purposes. For instance, in July 2018, Innovate UK, the UK’s innovation agency, funded approximately US$ 1.76 million (£1.3 million) project, Evonetix Ltd, (UK) that will be in partnership with Durham University. The funds will be used for the development of a new enzymatic approach to DNA synthesis. Moreover, in April 2018, DNA Script received approximately US$5.5 million in grant funds from the European Commission and Bpifrance (French investment bank). The technology platform, and other related resources are helping the company to accelerate the development of the gene synthesis. Companies have also increased their research and development funds for the enhancement of the gene synthesis. Additionally, in 2016, Twist Bioscience raised its revenue with US$ 61 million for the scale-up and commercial operation of the silicon chip-based high throughput low-cost gene synthesis platform.
The PCR technology is like the sunrise sector in the global healthcare and analytics arena. The growing inventions and innovation in the sector have continuing to accelerate worldwide. PCR is a nearly ubiquitous, powerful and reliable technology found in most molecular biology labs to amplify specific stretches of DNA for genotyping, cloning, analysis of single nucleotide variations and even serves as the basis for most next-generation sequencing (NGS) preparation. Technological advances are yielding different types of polymerase chain reaction (PCR) techniques. The use of PCR technology has now been explored into several non-conventional applications, making molecular diagnosis easier and faster. In particular, advances in digital and real time PCR are used to diagnose disease, identify bacteria and viruses, and aid forensic investigations.
dPCR and qPCR Market Segmental Overview
Based on technology, the dPCR and qPCR in healthcare market is segmented into QPCR and DPCR. The Quantitative PCR (qPCR) held the major market share among the technology segment in 2017, the Quantitative PCR (qPCR) segment held a largest market share of 55.9% of the dPCR and qPCR market, by technology. This segment is also expected to dominate the market in 2025 owing to its improved sensitivity, rapidity and reproducibility. It allows cost effective analysis with inexpensive kits and reagents. Furthermore, the digital PCR segment is anticipated to witness the fastest growth rate during the forecast period, 2018 to 2025.
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