To conduct this new business, various synthesis methods and techniques are required.
On May 29, 2019, one of the world’s leading chemical companies BOC Sciences announced to launch chemical building block service for the science community to support their needs arising from drug discovery process. To conduct this new business, various synthesis methods and techniques are required.
Pharmaceutical development is admittedly an extremely complex process that entails the discovery of numerous innovative active ingredients. Building blocks are important intermediates for many drugs that have major significance in drug discovery and synthesis. Many important substances and some natural drugs as well as synthetic drugs all contain heterocyclic structure, such as chlorophyll, heme, and nucleic acid.
“The heterocyclic compounds or heterocyclic compounds containing nitrogen atoms or fluorine atoms can be introduced into building blocks,” says Mr. Barron Jones, the Marketing Chief of BOC Sciences. “Further building blocks as intermediates can be used to synthesize the subsequent drugs or compounds, for the purpose of improving or changing the properties of the drugs or compounds. Besides, the introduction of sulfur and nitrogen-containing sulfonamide on the molecules of isopimaric acid can help broaden the range of effective anti-cancer activity of isopimaric acid. This benefit is very exciting.”
The simple idea is that through the introduction of some necessary groups, the properties of building blocks and the subsequent compounds can be changed. During the past decade, the synthesis of building blocks has been explored by numerous groups in pharmaceutical products as biologically active substances.
Biological routine and chemical routine are two main methods employed by scientists at BOC Sciences to conduct building block synthesis. Meanwhile, various types of other methods could also be used according to different needs. After the building block synthesis completed, multiple techniques (NMR, LCMS, GCMS, and X-ray) are used to analyze compounds.
In fact, building block synthesis belongs to a broad category, API synthesis, which covers intermediate synthesis, metabolites synthesis, impurities synthesis as well as reference compounds synthesis. For more information about BOC Sciences’ building block synthesis or custom synthesis service, please visit: https://www.solutions.bocsci.
About BOC Sciences
Dedicated to become a trust-worthy brand, BOC Sciences strives to offer strategies and solutions to assist in the resolution of the industry’s most pressing drug development issues. To this end, it provides comprehensive medicinal chemistry and drug testing service, custom synthesis, analysis/purification, formulation services for pharmaceutical companies engaged in drug discovery and research.