Single-Cell Sequencing Market Size Worth USD 3,230.6 Million by 2027 | Emergen Research

The global single-cell sequencing market is expected to reach USD 3,230.6 Million by 2027, according to a new report by Emergen Research. The market is projected to grow at a CAGR of 13.9% from 2020 to 2027. Single-cell sequencing is an approach used for the characterization of individual cells by sequencing the complete genomes, epigenomes, and transcriptomes. The technology aids in understanding how cell-to-cell variability contributes to phenotypic diversity in complex tissues and organisms.

The rising demand for personalized medicine is a major factor driving the growth of the market. In addition, the increasing adoption of single-cell sequencing in cancer research is another significant factor propelling the market growth. However, the lack of skilled professionals is expected to restraint the market growth over the forecast period.

Single-cell sequencing finds widespread use in cancer genomics, immunology, and neuroscience. However, there are still a few key challenges that need to be addressed for this technology to be adopted more widely by the scientific community. One of the key challenges is the high cost of single-cell sequencing. While the cost of sequencing has come down significantly in recent years, it is still quite expensive. This is one of the main reasons why single-cell sequencing has not been adopted more widely. Another challenge is the lack of standardization in protocols and reagents. This makes it difficult for scientists to compare results from different studies. Despite these challenges, single-cell sequencing is a powerful tool that is providing new insights into the biology of diseases. It is likely that this technology will continue to find new applications in the future.

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Increased investment in the R&D activities for the development of new sequencing technologies coupled with the government initiatives for the adoption of precision medicine is projected to fuel the growth of this market. However, dearth of trained personnel and high cost associated with these technologies are anticipated to restraint the growth of this market.

Some Key Highlights from the Report

  • Single-cell isolation aids in achieving cell viability of 99.0% without interfering with the cell physiology and function. This thus helps in obtaining accurate results from the sequencing reaction. Single-cell sequencing is used to obtain insights into various biological processes at a cellular level, thereby providing information about gene expression, epigenetics, cell identity, and taxonomy of cells. In addition, this technology also aids in studying rare populations of cells that are otherwise difficult to study using traditional methods.
  • The next-generation sequencing (NGS) technology has drawn attention in recent years for providing insights into the structure and function of genomes at a scale that was not possible before. However, this technology has its limitations when it comes to studying individual cells, owing to the heterogeneity that exists in cell populations. Single-cell sequencing can provide insights into gene expression at the resolution of an individual cell and is thus considered a powerful tool for studying cellular heterogeneity.
  • The instruments segment includes consumables, microfluidics, and sequencers. The consumables segment is expected to hold the largest share of the single-cell sequencing market in 2019. This can be attributed to the increasing adoption of next-generation sequencing (NGS) and the increasing demand for reagents & enzymes.
  • The microfluidics segment is anticipated to grow at a significant CAGR during the forecast period. This can be attributed to the advantages offered by microfluidics, such as miniaturization of workflows, multiplexing, and automation.
  • The sequencers segment includes long-read sequencers and short-read sequencers. The long-read sequencers segment is expected to hold the largest share of the single-cell sequencing market in 2019. This can be attributed to the increasing adoption of this technology for genome assembly and scaffolding.
  • Short-read sequencers are anticipated to grow at a significant CAGR during the forecast period. This can be attributed to the increasing adoption of this technology for de novo assembly and read mapping.
  • The applications segment includes target enrichment, copy number variation (CNV) analysis, DNA-seq, whole transcriptome sequencing (WTS), and chromatin accessibility sequencing (CAS). The target enrichment segment is expected to hold the largest share of the single-cell sequencing market in 2019. This can be attributed to the increasing adoption of this technology for cancer research and immune system profiling.
  • Key participants include Illumina, Thermo Fisher Scientific Inc., Fludigim, Bio-Rad, Becton, Dickinson, and Company, Qiagen, F Hoffmann-La Roche Ltd., BGI, 10X Genomics Inc., Oxford Nanopore Technologies, among others.

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Emergen Research has segmented the global single-cell sequencing market on the basis of product type, workflow, technology, disease type, application, end-use, and region:

Product Type Outlook (Revenue, USD Billion; 2017-2027)

  • Reagents
  • Instruments

Workflow Outlook (Revenue, USD Billion; 2017-2027)

  • Single Cell Isolation
  • Sample Preparation
  • Genomic Sequencing

Technology Outlook (Revenue, USD Billion; 2017-2027)

  • Sequencing
  • qPCR
  • Microarray
  • MDA
  • PCR

Disease Type Outlook (Revenue, USD Billion; 2017-2027)

  • Oncology
  • Immunology
  • Prenatal Diagnosis
  • Neurobiology
  • Microbiology
  • Others

Application Outlook (Revenue, USD Billion; 2017-2027)

  • Circulating Cells
  • Cell Differentiation/Reprogramming
  • Subpopulation Characterization
  • Genomic Variation
  • Others

End Use Outlook (Revenue, USD Billion; 2017-2027)

  • Academic & Research Laboratories
  • Hospitals & Clinics
  • Biopharmaceutical & Biotechnology Companies
  • Others

Regional Outlook (Revenue, USD Billion; 2017-2027)

  • North America
    1. U.S.
    2. Canada
  • Europe
    1. Germany
    2. UK
    3. France
    4. BENELUX
    5. Rest of Europe
  • Asia Pacific
    1. China
    2. Japan
    3. South Korea
    4. Rest of APAC
  • Latin America
    1. Brazil
    2. Rest of LATAM
  • MEA
    1. Saudi Arabia
    2. UAE
    3. Rest of MEA

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