Prader-Willi Syndrome (PWS) Market: Increase in investment to find innovative solution for the PWS to drive the market

Prader-Wili syndrome (PWS) is a rare genetic disorder, which causes problems in intellectual development, behavior, physical growth, mood, and eating. This rare genetic disorder occurs due to changes in chromosome 15, which is responsible for regulating the gene expression. Difficulty to control eating is a major symptom among people with PWS. Other symptoms include moderate to high learning disabilities, possess a compulsive behavior, outbursts, and stubbornness.

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Newborns with this disorder may have small hands and feet, almond shaped eyes, and a triangular mouth.  Other factors that define PWS included reduced development of genital organs, feeding difficulties, quick weight gain, uncontrollable overeating, and extremely weak muscles. The disorder also causes incomplete or delayed puberty among individuals of both sexes; therefore, they are unable to have children.

In many of the cases, the Prader-Wili syndrome is inherited. However, in some cases the anomaly can take place which can be caused due to malfunctioning of chromosome 15. This may be passed from one generation to the next, especially in maternal uniparental disomy and deletion in paternal chromosome 15. Genetic changes may occur randomly during the formation of reproductive cells or during early development of embryo. In such cases, affected people may or may not have a history of the disorder in their family.

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Prader-Willi Syndrome (PWS) Market – Competitive Landscape

Chong Kun Dang Pharmaceutical Corp

Founded in 1941, Chong Kun Dang is headquartered in Seoul, South Korea. Company is leading pharmaceutical & biotechnological company in Korea. Company offers range of prescription drugs for anti-diabetics, anticancer, anti-hypertension, health supplements, prebiotics and healthy beverage products. Few of the drugs for Prader-Willi Syndrome (PWS) treatment are under pipeline.  Chong Kun Dang Pharmaceutical Corp is the first Korean pharmaceutical company which has got U.S. FDA approval and which export some of the products to the U.S. market.

LG Life Sciences Ltd.

Founded in 2002, LG Life Sciences Ltd. is headquartered in Seoul, South Korea. The company specializes in specialty chemicals in South Korea and international market. Company also offers range of products in animal health products as well as pharmaceuticals. In pharmaceutical segment company offers treatment products for Prader-Wili syndrome, fertility treatment related products, hormones, viscosupplements used during the treatment of degenerative diseases, chemical vaccines etc.

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Prader-Willi Syndrome (PWS) Market – Dynamics

Growth hormone continues to be the major constituent of overall therapeutic contribution:-

Currently, pharmacological drugs and therapy for Prader-Willi Syndrome are concentrated primarily on the usage of human growth hormone (HGH) supplementation, which is permitted in the U.S. Supplementation of growth hormone continues is one of the major constituent of overall therapeutic contribution of the market due to nearly pervasive deficiency of growth hormone (GH) in patients suffering from PWS syndrome.  Accepted growth hormone therapies in North America and Europe include Genotropin by Pfizer, Nordotropin by Novo Nordisk, and Ominitrope (somatropin injection) from Sandoz. Growth hormone therapies which are increasingly used to treat PWS patients, especially older patients are central nervous system and cardiovascular agents.

Clinical Trials Pave the Way for PWS Treatments:-

Increase in investment to find innovative solution for the Prader-Willi syndrome (PWS) by pharmaceutical and biotech companies is expected to drive the market. Many clinical trials are taking place around the world which are helping to better understand syndrome and to develop novice products/ therapy for the treatment of PWS. However, side effects and high cost of these therapies are likely to hinder the global Prader-Willi syndrome market

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