Gene Synthesis Market Size to Hit US$ 10.58 Billion by 2030

The global Gene Synthesis Market size is expected to hit around US$ 10.58 billion by 2030 and is anticipated to grow at a CAGR of 19.1% during forecast period 2021 to 2030.

Growth Factors

Gene synthesis space is offering enormous potential for new biological functionality. This has resulted in the introduction of supportive government policies associated with synthetic biology, thereby driving the market.

Industry participants strive for developing proprietary and new technologies to strengthen their market presence. Furthermore, the establishment of organizations and forums helps encourage researchers to opt and study genetic engineering-related concepts and develop innovative technologies, which is also a notable growth driver of this space.

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Considering this space as a lucrative source of revenue, companies are focusing on collaborations with various universities for on-site training, online workshops, and sponsored projects to boost their expertise portfolio. This is also expected to generate interest among research professionals by helping them realize the potential of this field and therefore spurring adoption in the market.

By Method Analysis

The solid-phase synthesis segment captured the maximum revenue share of more than 36% in 2020 owing to the highest adoption rate over the past few years. Also, the high accuracy of this method further boosts its deployment among the therapy developers and research settings. 

PCR- and chip-based methods are anticipated to register significant CAGRs over the forecast period. These methods allow the synthesis of larger fragments at a lower rate, resulting in their increased usage.

Report Coverage

Report Scope	Details
Market Size	US$ 10.58 billion by 2030
Growth Rate	CAGR of 19.1% From 2021 to 2030
Largest Market	North America
Base Year	2021
Forecast Period	2021 to 2030
Segments Covered	Method, Service, Application, End use
Regional Scope	North America, Europe, Asia Pacific, Latin America, Middle East & Africa
Companies Mentioned	GenScript; GENEWIZ; Boster Biological Technology; Twist Bioscience; ProteoGenix; Biomatik; ProMab Biotechnologies, Inc.; Thermo Fisher Scientific, Inc.; Integrated DNA Technologies, Inc.; OriGene Technologies, Inc.

 

By Service Analysis

The antibody DNA synthesis segment led the market with a revenue share of more than 60% in 2020. The presence of a substantial number of market players offering services for antibody DNA synthesis has resulted in the dominance of this segment. 

Companies are offering services to pharma/biotech companies and research institutions to allow cloning and synthesis of antibody heavy/light chain sequences into any custom vector. On the other hand, the viral gene synthesis segment is estimated to register the fastest CAGR from 2021 to 2028 owing to the increasing virus vector-related R&D activities.

Companies are engaged in the synthesis of all non-structural and structural protein genes or gene fragments of the SARS-CoV-2. This has accelerated the acquisition of the virus recombinant proteins and has encouraged the research of protein structural biology of the virus particles. 

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By Application Analysis

The gene & cell therapy development segment accounted for the largest revenue share of more than 35% in 2020. This is anticipated to continue expanding the pipeline of advanced therapies for treating chronic conditions. 

Academic institutions and companies across the globe are actively engaged in the development of new therapies, which are likely to boost the demand for services in this market.

the companies are also focusing on investments and funding to extend their capabilities for stem cell therapies and regenerative medicines. On the other hand, the vaccine development segment is anticipated to witness the fastest CAGR from 2021 to 2028 due to the rising concerns regarding future pandemics.

By End-use Analysis

The academic and government research institutes segment dominated the global market in 2020 accounting for a revenue share of over 54%. The segment is estimated to expand further at the fastest CAGR from 2021 to 2028 owing to the high usage of gene synthesis services in research settings. 

The biotechnology & pharmaceutical companies segment is anticipated to witness notable growth during the forecast period. Increasing usage of synthesis biology by biotech companies for the development of novel disease management modalities is expected to bolster the segment growth.

By Regional Analysis

North America accounted for the largest revenue share of more than 38% in 2020 due to the presence of major players and supportive government initiatives pertaining to the training and implementation of synthetic biology programs.

Asia Pacific is estimated to register the fastest CAGR from 2021 to 2028. This can be attributed to the rising investments by global companies in the regional market. Moreover, the presence of some key companies in emerging nations, such as China and India, contributes to the market growth.

Key Players

• GenScript
• Brooks Automation, Inc. (GENEWIZ)
• Boster Biological Technology
• Twist Bioscience
• ProteoGenix
• Biomatik
• ProMab Biotechnologies, Inc.
• Thermo Fisher Scientific, Inc.
• Integrated DNA Technologies, Inc.
• OriGene Technologies, Inc. 

Market Segmentation

• By Method
  • Solid-phase Synthesis
  • Chip-based Synthesis
  • PCR-based Enzyme Synthesis
• By Service 
  • Antibody DNA Synthesis
  • Viral DNA Synthesis
  • Others
• By Application 
  • Gene & Cell Therapy Development
  • Vaccine Development
  • Disease Diagnosis
  • Others
• By End-use 
  • Biotechnology & Pharmaceutical Companies
  • Academic & Government Research Institutes
  • Contract Research Organizations
• Regional 
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa (MEA)

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