September 22, 2005 -- Antipsychotic drugs are big business. Together they have sales of over $10 billion annually. The introduction of antipsychotic drugs changed the practice of psychiatry in a major way. Perphenazine, a drug introduced in the 1950’s was one of the first in its class. Newer drugs now control the market, so a major study decided to see what they add. The answer is suprising...