According to Nova one advisor, the global Active Pharmaceutical Ingredient market size is expected to hit around USD 354.1 billion by 2030 from valued at USD 209.9 billion in 2021 and growing at a CAGR of 7.2% from 2022 to 2030.
According to Nova one advisor, the global Active Pharmaceutical Ingredient market size is expected to hit around USD 354.1 billion by 2030 from valued at USD 209.9 billion in 2021 and growing at a CAGR of 7.2% from 2022 to 2030.
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Key Takeaways:
- By Type of Synthesis, the U.S. Active Pharmaceutical Ingredient market was valued at USD 75.9 Billion in 2021 and expected to witness growth at a CAGR of 4.9% from 2022 to 2030.
- The innovative APIs segment dominated the market in terms of the revenue share of 67.3% in 2021, owing to increasing research and development activities for novel drug development and positive government initiatives
- The cardiovascular disease segment held the largest revenue share of 20.5% in 2021, attributed to the rising prevalence of target disease globally
- The synthetic API segment dominated the market with the largest revenue share of 72.6% in 2021, owing to the higher availability of raw materials and easier protocols for the synthesis of these molecules
- North America accounted for the largest revenue share of 40.0% in 2021 and is expected to maintain its lead over the forecast period. This is attributed to the rising epidemiology of cancer, along with other lifestyle-induced diseases, thus encouraging the R&D activities, thereby boosting the market growth
Report Scope of the Active Pharmaceutical Ingredient Market
Report Coverage |
Details |
Market Size |
USD 354.1 Billion by 2030 |
Growth Rate |
CAGR of 7.2% from 2022 to 2030 |
Largest Market |
North America |
Fastest Growing Market |
Asia Pacific |
Base Year |
2021 |
Forecast Period |
2022 to 2030 |
Segments Covered |
Type of synthesis, type of manufacturer, type, application and Region, |
Companies Mentioned |
Merck & Co., Inc.; AbbVie, Inc.; Bristol-Myers Squibb Company; Boehringer Ingelheim International GmbH; Teva Pharmaceutical Industries Ltd.; Cipla, Inc.; Albemarle Corporation; Viatris Inc.; Aurobindo Pharma; Sun Pharmaceutical Industries Ltd.; Dr. Reddy’s Laboratories Ltd. |
This aids in reducing costs and the risk of contamination. Artificial intelligence and protein synthesis are expected to facilitate faster development with greater control over the process.
The rising prevalence of chronic and lifestyle-based conditions, such as cardiovascular diseases, is accelerating the demand for API. For instance, as per U.S. Pharmacist in 2020, 47% of adults have at least one risk factor that supports cardiovascular disease development. Cardiovascular diseases are one of the global, critical public health burdens driving extensive R&D for APIs in the field.
The active pharmaceutical Ingredients market was positively influenced by the COVID-19 pandemic, as countries and significant players produce large quantities of components to meet the demand for the treatment of COVID-19. As a result of the outbreak, drug companies have changed the companies’ strategies to focus on a larger patient population. To treat coronavirus, the U.S., for example, requested that HCQ be imported from India. The virus has also impacted Canada's medicine supply system, potentially causing complications for patients. The increasing importance of generics, rise in consumption of biopharmaceuticals, and expanding drug research and development activities for drug manufacturing are the primary drivers driving the growth of the market. However, the market's expansion is likely to be hampered by unfavorable drug price control regimes in several countries and high manufacturing costs.
Developing nations like India are receiving an increased preference in the market over dominant API market countries, like China, owing to geopolitical situations. Furthermore, India has quality raw materials and products, a large workforce, a vast distribution network, and government subsidies through the "Make in India" program.
To address unmet medical needs, companies are collaborating to develop novel treatments. This allows firms to use their resources to aid in the development of products and enhance the supply chain. In November 2021, Merck & Co Inc. announced that it has acquired Acceleron Pharma, this acquisition would help Merck & Co to expand their cardiovascular portfolio and pipeline.
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Regional Insights
North America accounted for the largest revenue share of 40.0% in 2021 and is expected to maintain its lead over the forecast period. It is due to the rising incidence of cancer and other lifestyle-induced diseases, which stimulates R&D, thereby boosting the market.
Asia Pacific is anticipated to exhibit the fastest CAGR of 7.9% during the forecast period. The presence of economies such as China and India that the world relies on for the production of APIs at a lower cost is an advantage for the region. Increasing healthcare expenditure in the region is anticipated to fuel the market growth.
Europe is expected to witness significant growth during the forecast period. An increase in research funding and the local presence of key market players in this region is expected to drive the market. The number of biopharmaceutical companies is growing in Europe owing to increasing investments. For instance, in 2018, USD 20 billion was raised as an investment by the biopharma industry, which increased by 28% to USD 27.5 billion in 2019. Many key global players conduct their biopharmaceutical R&D in Europe.
Some of the prominent players in the Active Pharmaceutical Ingredient Market include:
- Merck & Co., Inc.
- AbbVie, Inc.
- Bristol-Myers Squibb Company
- Boehringer Ingelheim International GmbH
- Cipla, Inc.
- Teva Pharmaceutical Industries Ltd.
- Albemarle Corporation
- Viatris Inc.
- Aurobindo Pharma
- Sun Pharmaceutical Industries Ltd.
- Dr. Reddy’s Laboratories Ltd.
Segments Covered in the Report
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2017 to 2030. For this study, Nova one advisor, Inc. has segmented the global Active Pharmaceutical Ingredient market
- Type of Synthesis
- Biotech APIs Market, By Type
- Biotech APIs Market, By Type
- Generic APIs
- Innovative APIs
- Biotech APIs Market, By Product
- Monoclonal Antibodies
- Hormones
- Cytokines
- Recombinant Proteins
- Therapeutic Enzymes
- Vaccines
- Blood Factors
- Biotech APIs Market, By Type
- Synthetic
- Synthetic APIs Market, By Type
- Generic APIs
- Innovative APIs
- Synthetic APIs Market, By Type
- Biotech APIs Market, By Type
- Type of Manufacturer
- Captive APIs
- Merchant APIs
- Merchant APIs Market, By Type
- Generic APIs
- Innovative APIs
- Merchant APIs Market, By Type of Synthesis
- Biotech
- Synthetic
- Merchant APIs Market, By Type
- Type
- Generic APIs
- Innovative APIs
- Type of Drug
- Prescription Drugs
- Over-the-counter Drugs
- Application
- Cardiovascular Diseases
- Oncology
- CNS and Neurology
- Orthopedic
- Endocrinology
- Pulmonology
- Gastroenterology
- Nephrology
- Ophthalmology
- Others
By Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
Key Benefits for Stakeholders
- This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the global Active Pharmaceutical Ingredients industry analysis from 2022 to 2030 to identify the prevailing Active Pharmaceutical Ingredients industry opportunity.
- The market research is offered along with information related to key drivers, restraints, and opportunities.
- Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
- In-depth analysis of the global Active Pharmaceutical Ingredients industry segmentation assists to determine the prevailing market opportunities.
- Major countries in each region are mapped according to their revenue contribution to the global market.
- Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
- The report includes the analysis of the regional as well as global Active Pharmaceutical Ingredients industry trends, key players, market segments, application areas, and market growth strategies.
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