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Charles River Laboratories, Pathology Associates (PAI) 

15 Worman's Mill Court
Suite I
Frederick  Maryland  21701  U.S.A.
Phone: 301-663-1644 Fax: 301-663-8994

Charles River Laboratories, Pathology Associates (PAI) is the largest provider of contract toxicologic pathology services in the world. Since 1981, PAI has gained a solid reputation as providing highly skilled and collaborative pathology-based services, supporting biomedical research and testing programs sponsored by pharmaceutical, biotechnology, consumer product, biomedical device, and chemical industry clients, as well as government agencies.

The PAI Mission
To serve our clients with a commitment to scientific excellence, an appreciation for their vision, and with respect, loyalty and reliability.

PAI operates 5 full-service laboratories within the US. Each of the laboratories is equipped to provide Good Laboratory Practice (GLP)-compliant necropsy, histology and histopathology services, as well as a wide variety of specialty pathology-based disciplines such as electron microscopy, immunohistopathology, plastics histology and histomorphometry. Throughout these various locations, PAI maintains a staff of approximately 40 veterinary pathologists, with the majority boarded by the American College of Veterinary Pathologists (ACVP) and many of which have advanced research degrees (M.S. and/or Ph.D.).

PAI offers the following resources to support contract research, product development and safety assessment programs:

Molecular and Immunohistopathology
  • Monoclonal Antibody Characterization
  • Cell Proliferation and Apoptosis
  • Characterization of Tumor Xenografts
  • Screening for Biomarkers in Human Tissues
  • In situ Hybridization

Toxicologic Pathology
  • Necropsy
  • Histology
  • Histopathology
  • Peer Review

Specialty Pathology Disciplines
  • Medical Device Pathology
  • Bone / Hard Tissue Pathology
  • Developmental / Reproductive Pathology
  • Neuropathology
  • Electron Microscopy and Ultrastructural Techniques
  • Quantitative Image Analysis / Histomorphometry
  • Archive / Repository
  • Clinical Pathology

Last Updated: 02-10-05

Key Statistics

Ownership: Public

Web Site: Charles River Laboratories, Pathology Associates (PAI)
Employees: 7500
Symbol: CRL

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