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Approvals
Novartis Expands Spinal Muscular Atrophy Gene Therapy Market With FDA’s Itvisma Greenlight
The FDA approved an intrathecal form of Novartis’ spinal muscular atrophy gene therapy Zolgensma on Monday, broadening access to patients two years and older in what one Stanford Medicine professor called a “game changing advance” for the field.
November 25, 2025
·
2 min read
·
Heather McKenzie
Mergers & acquisitions
Avidity Played Hardball to Land Favorable Terms in $12B Novartis Deal
At one point in merger negotiations with Novartis, Avidity CEO Sarah Boyce and her team walked, cutting off access to a data room and moving on to a capital raise.
November 25, 2025
·
3 min read
·
Annalee Armstrong
Layoff Tracker
Novartis Cuts 550 Employees as Swiss Manufacturing Priorities Shift
Follow along as
BioSpace
tracks job cuts and restructuring initiatives.
November 25, 2025
·
92 min read
·
BioSpace Editorial Staff
Obesity
Novo Bounces Back With ‘Competitive’ Mid-Stage Weight Loss Data for Amycretin
Novo Nordisk’s amycretin showed no weight-loss plateau over 36 weeks in patients with type 2 diabetes, suggesting its efficacy could become even stronger with longer follow-up, according to analysts at BMO Capital Markets.
November 25, 2025
·
2 min read
·
Tristan Manalac
Weight loss
Lilly Redefines the Pharma Mega-Blockbuster
Previous mega blockbusters took years to reach their peak sales. Lilly’s tirzepatide franchise is on course to exceed them just a few years in.
November 25, 2025
·
2 min read
·
Annalee Armstrong
Cancer
Late-Stage Data For J&J’s Tecvayli/Darzalex Combo Could ‘Shift Paradigm’ in Myeloma
Tecvayli plus Darzalex led to an 83% boost to progression-free survival versus the current standard therapy in relapsed or refractory multiple myeloma, results analysts at Guggenheim Securities called “remarkable.”
November 25, 2025
·
2 min read
·
Tristan Manalac
FDA
Pazdur Questions Safety, Legality of FDA’s Expedited Drug Approval Programs
Richard Pazdur, the new director of the Center for Drug Evaluation and Research, raised concerns amid the rollout of several FDA initiatives seeking to shorten the drug review process.
November 25, 2025
·
2 min read
·
Tristan Manalac
Government
Former DARPA Official Jackson Named ARPA-H Head
Alicia Jackson formerly served as deputy director of the Biological Technologies Office at the Defense Advanced Research Projects Agency.
November 25, 2025
·
2 min read
·
Tristan Manalac
Press Releases
ANI Pharmaceuticals to Present at the Piper Sandler 37th Annual Healthcare Conference
November 25, 2025
·
1 min read
Press Releases
Catalyx Report Reveals Persistent Manufacturing Bottlenecks in Life Sciences Industry
November 25, 2025
·
4 min read
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