Find out why the NSG mouse is such a powerful tool in cancer, stem cell, diabetes, and other research. Join Jackson Laboratory scientists on Thursday, December 2, at 3:00 pm, ET, for a live webinar on the “Power of Modeling Human Disease in NSG Mice.” This webinar highlights key capabilities of this state-of-the-art immunodeficient host:
- Recapitulation of primary human tumors, including preservation of the tumor microenvironment for prolonged periods
- Human melanoma cell transplantation: engraftment of individual, unselected primary melanoma cells, showing 25% tumorigenic cells
- Normal differentiation of human epithelial stem cells following transplantation
- Support of a human immune system, including differentiation of all major cell types, B cells that undergo lg class-switching, and cytotoxic T cells that show HLA restriction
- Engraftment of human T cells infected by HIV for testing novel therapies
Register today at www.jax.org/jaxmice/webinar/nsg