WEDNESDAY, Aug. 4 (HealthDay News) -- Elevated levels of serum C-terminal propeptide of type I procollagen (PICP) are indicative of increased myocardial collagen synthesis in sarcomere-mutation carriers without overt hypertrophic cardiomyopathy, and often precede the development of left ventricular hypertrophy or fibrosis that is visible on imaging, according to a study in the Aug. 5 issue of the New England Journal of Medicine.
