Perfusion System Market Size to Worth Around USD 1.89 Billion by 2030

According to Vision Research Reports, The global perfusion system market was valued at USD 1.2 billion in 2021 and is projected to be worth around USD 1.89 billion by 2030, expanding at a compound annual growth rate (CAGR) of 5.2% from 2022 to 2030.

Key Takeaway

• North America dominated the perfusion systems market with the highest revenue share of more than 39% in 2021.
• However, the Asia Pacific region is projected to advance at the maximum CAGR of 5.5% during the forecast period.
• The cardiopulmonary perfusion system held the highest revenue share of more than 43% in 2021.
• The ex-vivo organ perfusion system accounted for almost 30% of the overall market share in 2021.
• The hypothermic segment accounted for the highest market share of more than 63% in 2021.
• On the other hand, the normothermic perfusion systems held about 37% of the segment share in 2021.

Factors such as the growing prevalence of chronic diseases and the rise in the number of organ transplants and multiple organ failures are anticipated to boost the market growth. In addition, increasing investments in cell-based research and a rise in biologics manufacturing are further expected to impel the growth of the perfusion system industry.

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There was a steep downfall in the sales of perfusion systems during the first half of the pandemic. The lockdowns and restrictions imposed by governments globally resulted in reduced patient visits to hospitals, a reduced number of surgeries, and a slowdown in R&D activities. However, with the increasing efforts of the government and healthcare professionals to curb the spread of the virus and prepare for similar events in the future, the market began to recover in 2021 and is expected to flourish during the forecast period.

The rising demand for organ transplantation is the major factor propelling the growth of the market. As per the data published by the United Network for Organ Sharing, in the United States, 113,379 people need a lifesaving organ transplant (total waiting list candidates) as of August 2019. The rising demand for organ transplantation is expected to increase the demand for reliable organ perfusion systems. In addition, there is a rising prevalence of cardiovascular and respiratory diseases across the globe boasting the demand for organ transplantation. As per the data published by the Division of Transplantation (DoT) of the Department of Health and Human Services, Health Resources and Services Administration’s Healthcare Systems Bureau, there were 3,408 heart transplants in 2018. Thus, owing to the rising demand for organ transplantation and an increase in the prevalence of cardiovascular and respiratory diseases the market is expected to witness high growth.

Organ Type Insights

The rising prevalence of chronic kidney diseases is the major factor driving the growth of the market. As per the National Institute of Diabetes and Digestive and Kidney Disease, the prevalence of Chronic Kidney Disease (CKD) in the United States is about 14%. Similarly, in the United Kingdom as per Kidney Research UK report 2018, it is estimated that 3 million lives are at risk, as a result of moderate to severe chronic kidney disease. An estimated, 1 million people in the United Kingdom have chronic kidney disease but are undiagnosed. Furthermore, machine perfusion techniques demonstrated several benefits when compared with cold storage techniques. Thus, owing to the all above-mentioned factors the market is expected to witness high growth over the forecast period.

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Scope of the Report

Application Insights

The cardiopulmonary perfusion system held the highest revenue share of more than 43% in 2021, aided by the increasing prevalence of cardiovascular & respiratory diseases and a rapid rise in the number of organ transplant procedures being carried out across the globe. Based on application, the perfusion system market is segmented into cardiovascular perfusion system, cell perfusion system, and ex-vivo organ perfusion system.

The ex-vivo organ perfusion system accounted for almost 30% of the overall market share in 2021. This is because the ex-vivo perfusion system has the capability to allow organs to survive longer outside the body and make immediate transplants less urgent. This further helps the number of organs available for transplant to grow.

The cardiopulmonary perfusion system is further classified into oxygenators, heart-lung machines, perfusion pumps, cannula, monitoring systems, and others. The oxygenator segment held the largest revenue share in 2021 owing to the rising incidences of cardiopulmonary failure.

The cell perfusion system is further segmented into bioreactor perfusion system, microfluidic perfusion system, gravity/pressure-driven perfusion system, and small mammal organ perfusion system. The bioreactor perfusion system dominated the cell perfusion system segment with the highest share in 2021. This is attributed to factors such as the rising demand for biological products and the constant need to increase product yield & reduce production costs.

The ex-vivo organ perfusion system is further segmented into hypothermic and normothermic. The hypothermic segment accounted for the highest market share of more than 63% in 2021. This can be attributed to the advantages that the hypothermic perfusion system offers, such as better long-term graft survival rates, the ability to provide metabolic support, and decreased vasospasm.

On the other hand, the normothermic perfusion systems held about 37% of the segment share in 2021. The subsegment is expected to experience steady growth during the forecast period, as it is not only beneficial in preserving extended criteria donor (ECD), but also offers the convenience of organ quality assessment.

Regional Insights

North America dominated the perfusion systems market with the highest revenue share of more than 39% in 2021. This is attributed to the enormous healthcare spending and advantageous health cover policies by both government and private insurers in the region. The growing number of organ donors is a major factor contributing to the growth of the regional perfusion systems demand. According to the Health Resources & Services Administration, in the U.S., more than 40,000 transplants were carried out in 2021. The United States is expected to be the largest perfusion system market owing to the rising technological advancements and the presence of better healthcare infrastructure. Furthermore, the rising prevalence of cardiovascular and respiratory diseases increasing the demand of perfusion systems. According to the data published by the United Network for Organ Sharing, there were 19,513 transplants performed as of June 2019. However, the high cost of transplantation and scarcity of donors is the major factor expected to hinder the growth of the market. Thus, owing to the all above-mentioned factors the market is expected to hold the largest market share.

However, the Asia Pacific region is projected to advance at the maximum CAGR of 5.5% during the forecast period. Factors such as an increase in the geriatric population, and the shift towards a sedentary lifestyle that is contributing to a rise in the prevalence of chronic diseases, are driving the growth of the market in this region. Various regional government initiatives are also anticipated to boost the growth of the perfusion systems market.

Moreover, in countries like India and China, the number of patients in need of an organ transplant is way higher than the number of organ donors, which is a cause of concern for the government and healthcare officials; therefore, these countries are focusing on developing various strategies to promote organ donation.

Key Players

• Getinge AB
• Medtronic, plc
• LivaNova
• Terumo Corporation
• Nipro Corporation
• XENIOS AG
• Repligen Corporation
• Spectrum Laboratories, Inc.
• Merck KGaA
• Harvard Bioscience, Inc.
• ALA Scientific Instruments, Inc.
• Lifeline Scientific, Inc.
• XVIVO Perfusion AB

Market Segmentation

By Technology

• Hypothermic
• Normothermic

By Organ Type

• Heart
• Lung
• Kidney
• Liver
• Others

By Application

• Cardiopulmonary Perfusion System
  • Oxygenators
  • Heart-lung Machine
  • Perfusion Pumps
  • Cannula
  • Monitoring System
  • Others
• Cell Perfusion System
  • Bioreactor Perfusion System
  • Microfluidic Perfusion System
  • Gravity/Pressure-driven Perfusion System
  • Small Mammal Organ Perfusion System
• Ex-vivo Organ Perfusion System

Regional Outlook

• • North America
  • Europe
  • Asia Pacific
  • Latin America
  • The Middle East and Africa

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