WINNIPEG, MANITOBA--(Marketwire - November 03, 2008) - Medicure Inc. (TSX: MPH), a cardiovascular focused, biopharmaceutical company, today announced the repayment of US$12 million in senior debt. The US$12 million is the remaining portion of the US$15.84 million term loan facility entered into in August 2006 with a syndicate of lenders, led by GE Canada Asset Finance Holding Company (formerly Merrill Lynch Capital Canada Inc.), and including Silicon Valley Bank and Oxford Finance Corporation, to finance Medicure's acquisition of the U.S. marketing rights to AGGRASTAT®.