Mayo Clinic Researchers Discover One Mechanism For Why Men And Women Differ In Immune Response

Decreasing testosterone boosts immunity because testosterone helps control T-lymphocytes, the attack cells of the immune system, according to Mayo Clinic-led research in laboratory animals. The findings appear in the Nov. 15 edition of the Journal of Immunology (http://www.jimmunol.org/future/173.10.shtml ). Collaborators include scientists from Roswell Park Cancer Institute, Buffalo, N.Y.; the Tumor Immunity and Tolerance Section of the Laboratory of Molecular Immunoregulation, National Cancer Institute; and Howard Hughes Medical Institute/Memorial Sloan-Kettering Cancer Center.