The global mastocytosis market registered a steady growth during 2021 and is expected to grow at a higher revenue CAGR over the forecast period.
The global mastocytosis market registered a steady growth during 2021 and is expected to grow at a higher revenue CAGR over the forecast period. Market growth is driven by a genetic history of mast cell disease, increased awareness among people, and improvement in healthcare infrastructure.
Mast cells, a type of immune cell, can accumulate in bones, intestines, and other organs as well as under the skin in a condition known as mastocytosis.
Various symptoms are brought on by this abnormal growth of mast cells, including GI problems such as diarrhea, itchy skin bumps, and bone pain. When patients come into contact with specific environmental triggers (a severe allergic reaction), their risk of anaphylaxis may rise (such as a bee sting). If untreated, mastocytosis in some cases can be fatally aggressive and does not spread by others.
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There are two types of mastocytosis systemic and cutaneous. Mastocytosis can affect both children and adults. Cutaneous mastocytosis usually appears in children who are below 2 years, while it affects both men and women roughly equally.
Some of the factors supporting market growth
Drivers
- The genetic history of mast cell disease is expected to be a major factor driving growth of the mastocytosis drug market during the forecast period
- Additionally, major pharmaceutical companies' increased investments in R&D to create new therapies for systemic mastocytosis disorders is fueling market growth
- Also, the market is likely to be driven by non-profit organizations and government associations that are heavily focused on raising awareness of systemic mastocytosis disorders
For instance, the fourth annual International Mastocytosis and Mast Cell Diseases Awareness Day will be held on October 20, 2021. #SpotOurSpots is a national campaign aimed at raising awareness of mast cell disease and providing hope to mast cell disease patients across Australia. The Australasian Mastocytosis Society (TAMS) believes that as general Australian public becomes more aware of mast cell disease, awareness, and understanding of both. mast cell diseases will grow, resulting in increased investments in research for more accurate diagnostics and better treatments
Restraining Factors
- Low diagnostic rates, lack of knowledge, and availability of its treatment, rising treatment costs, and side effects linked to various treatment drugs are all factors that will hinder mastocytosis market growth
Opportunities
- Rising research & development investments by key market players, with an increase in novel drug launches and approvals for mastocytosis treatment, create opportunities for other market players
- To save time and reduce R&D costs, most companies in the blood cancer drugs and mastocytosis market are aggressively investing in technologies such as Artificial Intelligence (AI). Simulation of human intelligence processes by machines, particularly computer systems, with potential to outperform human intelligence is known as AI. This technology, when compared to human analysis, aids in the study of large amount of chemical and biological data to uncover prospective drug candidates with higher success rates.
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Largest Market Share:
By region, the market is segmented into North America, Asia Pacific, Latin America, Middle East & Africa, and Europe.
In terms of market share and revenue, North America dominates the mastocytosis drugs market and will maintain its dominance throughout the forecast period. This is due to presence of major market players and rising healthcare expenditure, which will further propel market growth rate in this region.
Fastest growing Region:
Due to rising prevalence of systemic mastocytosis in emerging countries, such as India and China, and development of healthcare infrastructure in Asia Pacific is expected to grow during the forecast period.
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Key Market Trends and Innovation:
- AB Science’s drug candidate masitinib is in clinical phase 3, it is used in treatment of adult patients with Indolent Systemic Mastocytosis, which is expected to be completed till 2028
- Blueprint medicine’s drug candidate blu-263 is in clinical phase 3, it is used in the treatment of 16 years or older with Indolent Systemic Mastocytosis and monoclonal mast cell activation syndrome, which is expected to be completed till 2023
- Assistance Publique- H pitaux de Paris in collaboration with Centre of Reference for Mastocytosis (CEREMAST ) is investigating the drug Denosumab, which is in clinical phase 3, which is used in treatment of 18 years or older with systemic mastocytosis
Organic and Inorganic strategies adopted
- In June 2021, Blueprint Medicines Corporation’s drug candidate Apritinib (brand name Ayvakit) was approved by FDA for adult patients with advanced systemic mastocytosis, including mast cell leukemia, systemic mastocytosis with an associated hematological neoplasm and aggressive systemic mastocytosis
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Major Companies in the Market Include:
Key Players
- Merck & Co. Inc.
- Bausch Health Companies Inc.
- Sanofi S.A.
- Pfizer Inc.
- Mylan NV
- Teva Pharmaceutical Industries Ltd.
- Novartis AG
- Johnson & Johnson
- Bayer AG
- Mallinckrodt Pharmaceuticals
- EPI Health, LLC
- Kaleo Inc.
Start-Ups & Innovator Key Players
- Allogene Therapeutics
Detailed Segmentation of the Market
By Type (Revenue, USD Billion; 2019-2030)
- Cutaneous Mastocytosis
- Systemic Mastocytosis
By Route of Administration (Revenue, USD Billion; 2019-2030)
- Parenteral
- Oral
By Product (Revenue, USD Billion; 2019-2030)
- Others
- Tablets or Capsules
- Injection
By Drug (Revenue, USD Billion; 2019-2030)
- Mast Cell Stabilizers
- Epinephrine, Steroids
- Proton Pump Inhibitors
- Tyrosine Kinase Inhibitors
- Antihistamines
By End Users (Revenue, USD Billion; 2019-2030)
- Retail Pharmacy
- Online Pharmacy
- Hospital Pharmacy
By Distribution Channel (Revenue, USD Billion; 2019-2030)
- Offline
- Online
By Region (Revenue, USD Billion; 2019-2030)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- U.K.
- France
- Italy
- Spain
- Sweden
- BENELUX
- Rest of Europe
- Asia-Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- UAE
- South Africa
- Israel
- Rest of MEA
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