The global lung in vitro market size was USD 273.7 million in 2020 and is expected to register a robust CAGR of 17.9% during the forecast period.
The global lung in vitro market size was USD 273.7 million in 2020 and is expected to register a robust CAGR of 17.9% during the forecast period. Rising prevalence of lung infections such as COPD, asthma, and lung cancer, and increasing investments in drug development procedures are some key factors boosting global market revenue growth.
Lungs are one of the vital organs in the human body. Lung dysfunction has a negative impact on lung structure and can cause fatal effects. Animal models are commonly used to analyze lung malfunctioning and progression of lung diseases. Though animal testing is a prevalent model for drug testing and studying several diseases, adoption of in vitro models has been increasing in recent times.
Two prominent reasons for this maybe for reducing animal experimentation and animal models cannot fully replicate human lung structure. Lung in vitro models are cell models that signify diseased or normal lung physiology. They are established by culturing epithelial cells, macrophages, and dendritic cells. Developed in vitro lung models have been demonstrated to mimic morphology and functionality of lung tissues. Technological advancements in cell culturing techniques and introduction of new alternatives to animal testing models are primary factors increasing growth of the lung in vitro models market.
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Pharmaceutical and biotechnology companies, CROs, government and academic research institutes are some of the major consumers in the lung in vitro model market. In addition, high investments for research and development, government funds to promote in vitro model technology, and rising adoption of drug discovery activities are fueling global market revenue growth.
Moreover, increasing applications of in vitro models in regenerative medicines, oncology-based research, and tissue engineering are some key factors expected to boost market growth in the coming years.
Market Dynamics:
Driver: Rising prevalence of lung diseases and increasing research on lung disorders
The global lung in vitro models market is gaining tremendous popularity for the past couple of years. One of the major factors driving revenue growth is the rising prevalence of fatal lung dysfunctions such as Chronic Obstructive Pulmonary Disease (COPD), pneumonia, asthma, lung cancer, and Idiopathic Pulmonary Fibrosis (IPF). Researchers are utilizing advanced lung in vitro models to study lung diseases and discover new drug therapies. Technological advancements in cell culturing and rising adoption of in vitro models instead of animal testing models are boosting revenue growth. Moreover, increasing applications in regenerative medicine are expected to open lucrative opportunities for key players in the global market.
Restraint: Shortage of trained professionals is a major factor hampering growth of the global market
In spite of technological advancements in cell culturing techniques and development of 2D and 3D in vitro models, unavailability of trained personnel and skilled researchers to operate and set up experiments is a major factor expected to hamper market growth during the forecast period. Moreover, low penetration rate of lung in vitro models, high costs required for setting up in vitro techniques, and lack of awareness about the models, especially in the underdeveloped countries, are expected to limit growth of the global lung in vitro models market during the forecast period.
Type Outlook:
The global lung in vitro models market is segmented into 2D models and 3D models based on type. 3D models are further sub-segmented into in-house 3D Models and commercialized 3D models. The 3D models segment accounted for largest revenue share of 55% in 2020 and is expected to register significantly steady revenue growth rate throughout the forecast period. Growing popularity of 3D models and rising need for effective and enhanced lung in vitro models capable of mimicking in vivo physiology are key factors fueling growth of this segment. However, the 2D models segment is also expected to account for substantial market share and register fastest CAGR over the forecast period. 2D in vitro models are cost-effective and cells can be observed more easily in them as compared to 3D models. High market revenue share is attributed to rising demand for 2D models and cell lines in drug screening and for developing 3D models.
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Application Outlook:
Based on application, the global market is segmented into drug discovery, toxicology, 3D model development, basic research, physiological research, stem cell research, and regenerative medicine. The drug discovery segment accounted for largest revenue share and dominated other application segments in the global lung in vitro models market in 2020. High growth is attributed to rising investments in research and development of novel drugs, growing demand for in vitro models, and increasing adoption of lung in vitro model applications.
Regional Outlook:
North America accounted for largest market share of 36% in the global lung in vitro models market in 2020 and is expected to dominate other regional markets during the forecast period. Adoption of in vitro technology, dominance of key market players, increasing investments by leading companies for research and development activities, high funding from NIH, and well-developed health infrastructure are key factors augmenting growth of the lung in vitro models market in this region. The U.S. accounted for majority revenue share in the North America market due to favorable policies for healthcare, stringent laws for animal welfare, and a well-developed healthcare sector.
Asia Pacific market is projected to register a robust CAGR of 17.2% between 2021 and 2030. China and India are significant contributors in Asia Pacific. Factors such as increasing awareness about modern cell culturing techniques, presence of key market players, and increasing government initiatives and funds for medical infrastructure are fueling growth of lung in vitro models market in this region. Moreover, rising prevalence of lung disorders and growing awareness about lung diseases among people are expected to support revenue growth in the coming years.
Competitive Landscape:
The global lung in vitro models market is highly competitive and comprises several global and regional players. The leading players operating in the market include Epithelix (Switzerland), MatTek Corporation (US), Lonza (Switzerland), ATCC (US), InSphero (Switzerland), Emulate (US), AlveoliX (Switzerland), Oncotheis (Switzerland, TissUse (Switzerland), Mimetas (Netherlands), and CN Bio Innovations (UK). To strengthen their position in the global market, key players are focusing on implementing various strategies such as product launches, collaborations, joint ventures, and partnerships with other major companies.
This report offers historical data points and forecasts and revenue growth at a global, regional, and country-level, and provides analysis, industry trends, and consumption pattern details for each region, major country, and segment from 2018 to 2030. For this study, Reports and Data has segmented the global lung in vitro market based on type, application, and region:
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Lung In Vitro Model Market Report Scope
Segments covered By Based On Type, Based On Application, Regional Outlook
By Based On Type
- 2D Models
- 3D Models
- In-house 3D Models
- Commercialized 3D Models
By Based On Application
- Drug Discovery
- Toxicology
- 3D Model Development
- Basic Research
- Physiological Research
- Stem Cell Research and Regenerative Medicine
Regional scope
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
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