Wilmington, Delaware, United States, Transparency Market Research Inc.: The pigmentation biology has made considerable strides over the decades, anchored broadly by evolution, developmental biology, and genetics.
Wilmington, Delaware, United States, Transparency Market Research Inc.: The pigmentation biology has made considerable strides over the decades, anchored broadly by evolution, developmental biology, and genetics. A significant percentage of all dermatological consultations in a number of countries around the world is motivated by cutaneous hyperpigmentations, with most common complaints between 15 and 30 years of age, regardless of color, gender, and skin.
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Hyperpigmentations are a group of diseases that can be acquired or congenital, and the symptoms are associated with alterations in the melanin pigment. Key group of disorders that have been propelling revenues in the hyperpigmentation disorders treatment market are postinflammatory hyperpigmentation, solar lentigines, melasma, ephelides (or freckles), and macules. Various treatments either as standalone or a combination of any two or more have been researched for the treatment of hyperpigmentation. Melasma and vitiligo are by far the most common disorders. Most of the conditions appear to be benign but are aesthetically distressing condition.
The global hyperpigmentation disorders treatment market was pegged at US$ 3,947.3 Mn in 2017. It is projected to clock CAGR of more than 7.2% during the forecast period of 2018 to 2026. This is projected to reach worth of US$ 7,225.6 Mn by 2026. The growing incidence of pigmentation disorders in the elderly is a key driver for prospects in the market.
Major treatment types that stir revenue generation in the global hyperpigmentation disorders treatment market are topical drugs, laser therapy, chemical peels, phototherapy, and microdermabrasion.
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Melasma Highly Lucrative Segment in Hyperpigmentation Disorders Treatment Market
A number of histological and immunohistochemical studies have expanded the researchers’ understanding of the pathogenesis of melasma, thus enriching the landscape of the hyperpigmentation disorders treatment market. Some of the key treatment avenues are topical hydroquinone (HQ), retinoic acid (RA), glycolic acid (GA) (double combination), and topical corticosteroid (triple combination) in double as well as triple combinations. On the back of R&D on these treatment avenues, the melasma was the leading disease indication segment in 2017.
It is predominant in women but is also significant in men across all ethnic and racial groups. This is prevalent in populations exposed to UV rays. In addition to UV exposure, various causative factors are involved. The demand for treatments is high in Asia Pacific, notably in Asian nations. A number of studies have been done to assess the demand in China, India, and Korea. Several studies have been found high prevalence of hyperpigmentation disorders in India, mainly due to prevalent sun-exposed environments. In the country, melasma can be attributed to or exacerbated by UV exposures. Upcoming therapies for melasma are likely to target prospects in this hyperpigmentation disorders treatment market and might open lucrative avenues. Advances in molecular genetics of human pigmentation disorders are enriching the landscape.
Other causes are estrogen levels, genetic predisposition, and phototoxic drugs; genetic predisposition might also play a role in causing melasma.
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Effectiveness of Laser Therapies in Hyperpigmentation Disorders Treatment Market Underpin High Acceptance Among Patients
The demand for treatments of post-inflammatory hyperpigmentation (PIH) is a key accelerant for new avenues in the hyperpigmentation disorders treatment market. The prevalence of people with higher skin phototypes. Despite a large body of studies on PIH pathogenesis, currently there is an unmet need, which is expected to be capitalized by emerging and established players in the global hyperpigmentation disorders treatment market. A number of formulations such as hydroquinone, tretinoin, and dexamethasone are being explored to bridge this gap.
The growing effectiveness of laser therapies in the treatment of hyperpigmentation, such as dark circles or periorbital hyperpigmentation (POH), has generated massive revenue potential in the hyperpigmentation disorders treatment market. The patient’s acceptance of laser therapies has increased in recent years. Key of them are QS ruby laser-based treatments. The prevalent use of fractional laser photothermolysis in the treatment of disorders is a key factor bolstering the sales revenues in the hyperpigmentation disorders treatment market.
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Over the years, new data on hyperpigmentation disorders have emerged, and still continue to enrich the landscape of the hyperpigmentation disorders treatment market. Subsequently, systemic use of corticosteroids, griseofulvin, antibiotics, isoniazid, antimalarials, psychotherapy, and phototherapy have boosted the hyperpigmentation disorders market.
Apart from the laser therapy, topical depigmenting agents have been extensively publicised in the hyperpigmentation disorders treatment market. These drugs aim at reducing the amount of melanin content. Topical drugs have been publicised in the treatment of cervical idiopathic poikiloderma or poikiloderma of Civatte (PC). The chronic nature of PC is a key driver for the need.
Various dermatology companies are harnessing the potential of several topical agents in newly launched products in the hyperpigmentation disorders treatment market. Of note, they have extensively marketed hydroquinone (HQ), a hydroxyphenol, for the treatment of PIH. In recent years, more studies have been done particularly in relation to developing topical retinoids for the treatment of melasma and actinic lentigines. Popular agents in some of the recent array of products in the market include soy extracts, mulberroside F, licorice extract, N-acetyl glucosamine, resveratrol, rucinol,niacinamide, and dioic acid.
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Asia Pacific Expected to Gain Share in Hyperpigmentation Disorders Treatment Market
The various regional markets are Europe, North America, Asia Pacific, the Middle East & Africa, and Latin America. Of these, Asia Pacific held a major share of the global hyperpigmentation disorders treatment market in 2017. The Asia Pacific hyperpigmentation disorders treatment market is anticipated to gain share by the end of the forecast period. New revenue streams are expected to emerge from the economies of the Middle East, Latin America, and Africa.
Some of the key players in the hyperpigmentation disorders treatment market are Vivier Pharma, Obagi Cosmeceuticals LLC, RXi Pharmaceuticals Corporation, EpiPharm AG, Pierre Fabre, SkinCeuticals, Galderma S.A., ALLERGAN, and Bayer AG.
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