Medical News Today -- Enzon Pharmaceuticals, Inc. (Nasdaq: ENZN) announced the publication of preclinical data demonstrating that PEG-SN38 (EZN-2208), the Company’s novel PEGylated DNA topoisomerase I inhibitor, led to significantly greater tumor regression as compared to CPT-11 (irinotecan) in both in vitro and in vivo models of pediatric neuroblastoma. The data were published in the October 1, 2010 issue of Clinical Cancer Research (Pastorino, F. et al, volume 16, number 9, pp. 4809-4821).
