LBP-1a Gene Mutation Linked To Disruption Of Normal Fetal Development

The lack of a gene called LBP-1a in the mouse embryo prevents normal growth of blood vessels in the placenta. This finding suggests that a similar defect in humans could play a role in fetal growth retardation, infant mortality and spontaneous abortion. These results, by investigators at St. Jude Children’s Research Hospital, are published in the August issue of Molecular and Cellular Biology (MCB).

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