BioSpace News Archive

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Cancer

Merck, Boehringer Ingelheim, More To Present Key Data at AACR ’25

Presentations at this year’s American Association for Cancer Research meeting could have a broad impact on the treatment landscape for head and neck and lung cancer, and implications for specific drug modalities like TIGIT and VEGF.

April 25, 2025

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4 min read

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Tristan Manalac

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Immunology and inflammation

Vyne Crashes After Safety Signal in Dogs Puts Hold on Clinical Trial of Plaque Psoriasis

The hold, placed by the FDA on an early-stage clinical trial of an experimental BET inhibitor, stems from a recent observation of testicular toxicity in canines given the treatment.

April 25, 2025

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2 min read

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Tristan Manalac

Earnings

Gilead’s PrEP Launch Full Speed Ahead Despite Macro Pressures on HIV Space

Despite steep budget and staffing cuts at the FDA in recent weeks and other headwinds, Gilead CEO Daniel O’Day assured investors that the pharma’s plans and preparations for lenacapavir’s launch remain on track.

April 25, 2025

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3 min read

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Tristan Manalac

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Legal

Judge Rules Against Semaglutide Compounders After Shortage Declared Over

Big compounders will have until May 22 to stop producing and dispensing compounded semaglutide, while smaller, state-run pharmacies must immediately stop making copies of the blockbuster drug.

April 25, 2025

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2 min read

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Tristan Manalac

screenshot of Marty Makary speaking on the Megyn Kelly Show

FDA

Fact or Fiction? Unpacking FDA Commissioner Marty Makary’s First Interviews

As Marty Makary nears the end of his first month on the job, the FDA Commissioner sat down for two interviews, offering statements that alternatively contradict and jibe with reported events.

April 25, 2025

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7 min read

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Heather McKenzie

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Earnings

AbbVie Criticizes Trump’s Drug Pricing Proposal, Deflects Tariff Concerns

While AbbVie handily beat expectations this quarter, the company faces declining Humira sales and a challenged aesthetics business, plus the same macro headwinds blowing against the entire industry.

April 25, 2025

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3 min read

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Annalee Armstrong

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Layoffs

Caribou Changes Course Again, Lays Off 32% of Workforce

The cell and gene therapy company is cutting 47 employees and its entire lupus program to focus resources on two CAR Ts. The move follows a reconfiguration last year to move into immunology.

April 25, 2025

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1 min read

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Dan Samorodnitsky

Press Releases

Pyxis Oncology Presents Promising Preclinical Results Providing Proof of Mechanism of Micvotabart Pelidotin, the First-in-Concept Extracellular-Targeting ADC

April 25, 2025

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8 min read

Press Releases

T-knife Therapeutics Presents Preclinical Data at the American Association for Cancer Research (AACR) Annual Meeting Demonstrating a Potential Best-in-Class PRAME Targeted TCR-T Therapy