BioSpace News Archive

Contemporary art collage. Hand put money to golden stack of coins, meaning income from investment. Concept of business strategy, investment, development, market, finance.

Merck KGaA Moves Ahead on SpringWorks Buy for $3.9B

The transaction is expected to close in the second half of 2025. With the deal, Merck KGaA is adding to its rare disease and oncology pipelines.

April 28, 2025

·

3 min read

·

Tristan Manalac

Bladder cancer

J&J Declares ‘Sustained Disease Control’ With Bladder Cancer Drug-Device Combo

The targeted drug release device TAR-200 shows promising response and disease-free survival rates in specific populations of patients with non-muscle-invasive bladder cancer.

April 28, 2025

·

2 min read

·

Tristan Manalac

A monoclonal antibody (mAb or moAb) is an antibody made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Coronavirus. 3d render

Bladder cancer

Pfizer’s Subcutaneous PD-1 Cuts Risks in Bladder Cancer but Misses Survival Endpoint

Pfizer’s sasanlimab, when used with standard of care, reduced the likelihood of disease recurrence or progression, death due to any cause or persistence of cancer cells by 32% in patients with high-risk non-muscle invasive bladder cancer.

April 28, 2025

·

1 min read

·

Tristan Manalac

Employees Walking In And Out Of The Door, Some Were Leaving Their Job And Some Were Being Hired At The Same Time. Full Length, Isolated On Solid Color Background. Vector, Illustration, Flat Design, Character.

Layoffs

Spruce Axes 55% of Staff, Leaving Shoestring Crew To Focus on New Rare Disease Asset

Spruce Biosciences is cutting over half of its employees as it looks to secure accelerated approval of a Sanfilippo syndrome therapy it recently acquired from BioMarin.

April 28, 2025

·

1 min read

·

Angela Gabriel

FDA

Cell and Gene Therapy Sector Enters ‘Critical’ Period After Marks’ FDA Exit

As tariffs, HHS workforce cuts and the ouster of CBER Director Peter Marks threaten the “lifeblood” of the cell and gene therapy space, experts express wariness over the unknowns and optimism that Marks’ legacy will carry on.

April 28, 2025

·

7 min read

·

Heather McKenzie