Preclinical

In writing literally hundreds of stories this year, two BioSpace writers, Alex Keown and Mark Terry, found certain stories particularly intriguing or impactful. Some of those were such big topics that they were covered over a series of stories. Looking back at 2018, here are their Top 10.
There are plenty of great scientific research stories out this week. Here’s a look at just a few of them.
A recent study published in CA: A Cancer Journal for Clinicians, a peer-review journal of the American Cancer Society, links excess body weight to approximately 4 percent of cancers worldwide.
A group of researchers from UCLA have developed a spray gel that contains immune-stimulating drugs. The gel was effective about 50 percent of the time in stimulating laboratory animals’ immune systems to stop cancer from recurring and inhibiting its metastases.
It seems like every time we turned around this year, there was an exciting or—on a more visceral level, “Hey, that’s cool!” science story. Here’s a look at the top 9 really cool life science discoveries of the year, from outer space, to peanut allergies, to tortoise genomes.
Researchers published an article in the journal Nature Ecology & Evolution that described preliminary findings of gene variants in George associated with a strong immune system, efficient DNA repair and cancer resistance.
There are plenty of great scientific research stories out this week. Here’s a look at just a few of them.
Talk about a welcome Christmas present! Researchers at Flinders University in Australia, working with mice, removed a single gene known as RCAN1 and then fed them a variety of diets, including a high-fat diet. The mice did not gain weight, even after dramatically overeating high-fat foods over several weeks.
Nuformix, the pharmaceutical development company using cocrystal technology to unlock the therapeutic potential of approved small molecule drugs, announces results from the completion of its innovative pre-clinical trial for its NXP002 fibrosis programme in human idiopathic pulmonary fibrosis (‘IPF’) against standard of care
Researchers with the University of California – Los Angeles Health Sciences have identified two major groups of genes that, when mutated, results in overproduction of the tau protein, at least in mice. They published their research in the journal Nature Medicine.
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