NIH Launches Study Of Hematopoietic Stem Cell Transplantation For Severe, Treatment-Resistant Lupus

Researchers at the Department of Health and Human Services’ National Institutes of Health (NIH) have launched a five-year study to see whether a therapy using transplantation of hematopoietic stem cells, blood stem cells found in bone marrow, can produce long-term remission for patients with severe, treatment-resistant systemic lupus erythematosus (or lupus), a rheumatic autoimmune disease that can affect the body’s major organs. The study will include a basic research component to examine the roles of B and T cells, white blood cells in the immune system, in triggering lupus symptoms.