The microcarrier market size was USD 1.4 Billion in 2020 and is expected to register a CAGR of 10.5% during the forecast period.
The microcarrier market size was USD 1.4 Billion in 2020 and is expected to register a CAGR of 10.5% during the forecast period. Market revenue growth is driven by key factors such as increasing R&D expenditure by pharmaceutical and biotechnology companies and rapid developments across the cell therapy industry.A microcarrier is a non-toxic finely particulate material used to grow cells in a suspension or a support matrix, which facilitates the growth of adherent cells in a bioreactor.
Microcarriers are composed of a solid matrix that are separated from expanded cells during downstream processing. The development of microcarriers with various physiochemical properties enable controlled cell and protein associations that are useful for novel therapeutics. Ease of scale-up, the ability to correctly control cell growth conditions in sophisticated, computer-controlled bioreactors, an overall reduction in floor space and the number of incubators required for a given-sized production process, and a drastic reduction in technician labor are advantages that would further increase the use of microcarriers in pharmaceutical and biotechnology industries.
Microcarriers Market: Dynamics
Advantages of microcarriers and application in cell development to drive market growth
Increasing demand for stem cell therapy coupled with rising prevalence of cancer across the globe will drive microcarriers market growth. One of the leading drivers of market revenue growth is increasing incidence of diseases where cell therapy can be effectively applied. World Health Organization (WHO) estimates that the global burden of cancer is predicted to rise to 27.5 million new cases and 16.3 million deaths by 2040. Increasing funding for the biopharmaceutical industry and technological advancements in microcarrier development have contributed to growth of the market. For instance, researchers from the Singapore-MIT Alliance for Science and Technology (SMART), have developed a novel microcarrier for large-scale cell production and expansion that provides higher yield and cost-effectiveness than conventional methods while reducing the number of steps needed in the cell retrieval process.
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The newly developed dissolvable gelatin-based microcarrier from SMART has shown to be effective for cell expansion in the treatment of a variety of ailments, including bone and cartilage defects as well as the body\'s rejection of foreign bone marrow and cells (called graft vs. host disease). In addition, the microcarriers\' dissolvability removes the need for a second separation stage to remove the cells from the microcarriers. This simplifies cell manufacturing while also improving the ease with which therapeutic cells can be processed for use in patient products. Rising demand for cell therapies will propel revenue growth of the microcarriers market going forward.
High cost of cell based R&D to drive market growth
Various academic institutes and small-scale companies with limited budgets cannot afford to conduct cell biology research as it involves extensive R&D, which demands highest quality of equipment, media, reagents, and other products. Microcarriers are mainly used in stem cell biology, which is a factor that is expected to restrain market growth. In addition, the need to comply with strict guidelines by regulatory bodies has driven up the cost of cell biology, thus creating additional challenges for microcarriers market growth.
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Product Outlook:
On the basis of product, the market is segmented into consumables and equipment. Consumables accounted for largest market share in 2020 among other product segments. Increasing adoption of microcarrier beads, media, and reagents for various cell culture procedures and applications is estimated to support revenue growth of the consumables segment during the forecast period.
Application Outlook:
On the basis of application, the global microcarriers market is segmented into vaccine manufacturing, cell therapy, and others. Vaccine manufacturing accounted for largest market revenue share in 2020 among other application segments. It is expected to account for a significant share due to surge in demand for cell-based vaccines. The ongoing COVID-19 pandemic has also added a considerable boost to growth of the vaccine manufacturing segment.
End Use Outlook:
On the basis of end-use, the global microcarriers market is segmented into pharmaceutical and biotechnology companies, research institutes, and CROs. Pharmaceutical and biotechnology companies accounted for the largest market share in 2020. The large share of this segment can be attributed to rising awareness about the benefits of cell-based vaccines and growing regulatory approvals for cell-based vaccines.
Regional Outlook:
The North America microcarriers market is expected to account for the largest revenue share in 2030 owing to increasing cell therapy research in this region. Gene and cell therapy is a considerable field of research and is receiving funds from both public and private sectors. For instance, nearly USD 20 billion in funding flowed into biotech companies developing cell-, gene- and tissue-based therapies in 2020, widely eclipsing the total amount invested in 2019 and ending up 50% higher than the previous record of USD 13.5 billion set in 2018.
Similar trend has been noted in Asia Pacific as well where research funding has been increasing as the region is increasing its R&D expenditure. For instance, China has established itself as a global leader in gene and cell therapy growth, ranking second in the world with over 1,000 clinical trials completed or in progress, as well as thousands of related patents issued by the Chinese government between 2017 and 2019. In addition to this, the country has a thriving gene and cell therapy biotech market, which is led by over 45 local companies and four foreign-participated collaborations with licensed gene and cell therapy pipelines.
The COVID-19 pandemic has driven growth of the vaccine manufacturing industry in 2020. India has become a prominent player in the vaccine manufacturing space. However, India is not self-reliant in some of these vaccine raw materials. Therefore in April 2021, Bharat Biotech International, Biovet, and Sapigen Biologix signed a joint Master Collaborative Agreement (MCA) with CSIR-Indian Institute of Chemical Technology (CSIR-IICT) to work on developing novel platform technologies for bio-therapeutics and vaccines to support affordable healthcare solutions. The collaboration would investigate chemicals and raw material including microcarriers, which are often in short supply. Increased investments in novel therapeutic development is expected to drive microcarriers market revenue growth in Asia Pacific in the coming years.
Competitive Landscape:
Some prominent players in the microcarriers market include Thermo Fisher Scientific, Corning, Merck, Sartorius, Danaher Corporation, Becton, Dickinson And Company, Eppendorf Ag, Lonza Group, Getinge Ab, Chemometec, Cesco Bioengineering, Himedia Laboratories, Esco Vaccixcell, Stemcell Technologies, Solida Biotech, Stobbe Pharma, Distek, Celltainer Biotech, G&g Technologies, and Tantti.
Segments Covered in the Report:
This report offers historical data points & forecasts and revenue growth at a global, regional, and country level, and provides analysis, industry trends, and consumption pattern details for each region, major country, and segment from 2018 to 2030. The global microcarriers market report includes industry trends, drivers, restraints, opportunities, threats, market strategies, segment revenue, and market share contribution by each regional and country market. In addition, the report offers industry analysis and competitive landscape, company financials, and impact analysis.
The report includes a detailed view of the global microcarriers market along with changing dynamics and trends, scenarios, detailed market and regional segmentation, regional landscape, analysis and evaluation, major investments, product offerings, product launches, and details of historical, current, and projected revenues.
For the purpose of this report, Reports and Data has segmented the global microcarriers market on the basis of product, application, end use, and region:
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Microcarrier Market Report Scope
Segments covered By Product Outlook, Application Outlook, End Use Outlook, Regional Outlook
By Product Outlook
- Consumables
- Media
- Sera/Serum-based Media
- Serum-free Media
- Other Media
- Reagents
- Microcarriers
- Collagen-coated Microcarriers
- Cationic Microcarriers
- Protein-coated Microcarriers
- Untreated Microcarriers
- Other Microcarriers
- Equipment
- Bioreactors
- Single-use Bioreactors
- Stainless-steel Bioreactors
- Culture Vessels
- Filtration and Separation Equipment
- Cell Counters
- Other Equipment
By Application Outlook
- Biopharmaceutical Production
- Vaccine Production
- Therapeutic Protein Production
- Cell and Gene Therapy
- Tissue Engineering and Regenerative Medicine
- Other Applications
By Source Outlook
- Pharmaceutical & Biotechnology Companies
- Contract Research Organizations & Contract Manufacturing Organizations
- Academic and Research Institutes
- Cell Banks
Regional scope
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
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