The global glycomics/glycobiology market size was USD 1.0 Billion in 2020 and is expected to register a CAGR of 14.1% during the forecast period.
The global glycomics/glycobiology market size was USD 1.0 Billion in 2020 and is expected to register a CAGR of 14.1% during the forecast period. Rising investments in research by pharmaceutical and biotechnology companies, development of novel drugs and therapeutics, rapid progress in proteomics, and increasing research in the glycomics field are key factors expected to drive market revenue growth over the forecast period.
Rising investment by government and private organizations to boost scope of glycomics research in academic institutes is also a key factor expected to drive revenue growth of the market over the forecast period. Increasing R&D activities to develop novel and efficient therapies to meet unmet medical needs across the globe has boosted demand for new glycomics and glycobiology tools and this is expected to further contribute to revenue growth of the market over the forecast period.
Glycomics, which is a subset of glycobiology, is a comprehensive study of glycomes and is generally defined as systematic study of all glycan structures in any cell or organism. Glycomics is an emerging field of research and has a wide range of applications in diagnostics, oncology, drug discovery and development, and immunology, among others. Glycomics or glycobiology studies structure, biology, and function of saccharides or glycans, whether free or present in complex molecules. It also studies genetic, physiologic, pathologic, and other aspects. Glycoproteins or glycolipids found on the surface of the cells play a crucial role in bacterial and viral recognition. Glycans are crucial for innate immunity, are involved in cellular signaling pathways, affect the stability and folding of proteins, and modulate cell functions. They also determine development of cancer cells and regulate cell regulation and invasion and inhibit proliferation. Glycomics is an integral part of microbiology research as glycans have diverse roles in bacterial physiology. Extensive research in bacterial glycomics has led to the development of novel drugs, glycoconjugate vaccines, and bioactive glycans. Inherent complexity of glycans and their complete structural analysis is a complex field. Recent technological advances in glycomics tools have enabled scientists clearly understand the importance of glycans in biology and this trend is expected to continue over the forecast period.
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Alterations in cell surface glycans contribute to metastatic and neoplastic properties of tumor cells and they play a crucial role in cancer biology. Increasing application of glycobiology in cancer research and extensive R&D to develop advanced products is expected to drive revenue growth of the market over the forecast period. Rising use of glycans in drug discovery and development and in therapeutic monoclonal antibodies is also a key factor expected to drive market revenue growth over the forecast period. However, high costs associated with glycomics tools and high complexity of glycomes are expected to restrain market growth to a certain extent over the forecast period.
Market Dynamics:
Driver: Increasing R&D investment in drug discovery and development is a key market revenue driving factor
Glycomics is crucial in microbiology research and extensive R&D in bacterial genomics has resulted in the development of novel drugs and glycoconjugate vaccines. Some of the important drugs, such as anti-flu virus drugs, available in the market have been developed through glycomics. Many recombinant pharmaceuticals such as therapeutic monoclonal antibodies are glycoproetins and this has led to the pharmaceutical industry and drug regulatory bodies understand the critical importance of glycans in therapeutics. This trend is expected to continue going ahead and is expected to contribute to revenue growth of the market over the forecast period. Increasing demand for precision medicine to treat chronic and rare diseases and meet the unmet clinical demands across the globe have propelled the companies to invest heavily in the pharma and biotech sector. This is expected to accelerate drug discovery and development processes and further fuel revenue growth of the market over the forecast period.
Restraint: High cost of glycomics tools is a key factor restraining market growth
The most commonly applied methods for glycan analysis are high-resolution mass spectrometry (MS) and high-performance liquid chromatography (HLPC). Instruments required for these procedures are generally expensive. Regulation and maintenance of these devices is also costly and this can act as a restraining factor for the market growth over the forecast period. X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy for comprehensive analysis of complex glycans is costly, complicated, and time-consuming. These factors are expected to restrain market growth to a certain extent over the forecast period.
Products Outlook:
Based on product, the global glycomics/glycobiology market has been segmented into enzymes, instruments, kits, and reagents. Enzymes segment is expected to account for significant revenue share in the global market over the forecast period owing to increasing use of enzymes in cancer research and diagnostics. Enzymes can be further segmented into glycosidases, neuraminidases, glycosyltransferases, sialyltransferases, and others. Glycosidases have been extensively studied in oncology research owing to their ability to alter N-linked gylcans in cancer cells and viruses. These enzymes are used in therapeutic approaches for diseases caused by deficiencies such as diabetes, Tay-Sachs disease, and Gaucher disease. Their therapeutic use also include direct antiviral, anti-cancer, and anti-bacterial activities. This is expected to contribute significantly to the revenue growth of the enzymes segment over the forecast period.
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Application Outlook:
Based on application, the global glycomics/glycobiology market has been segmented into drug discovery & development, diagnostics, and others. Drug discovery and development segment is expected to register rapid revenue CAGR over the forecast period attributable to increasing demand for glycomics products in drug discovery and development, extensive R&D activities in biopharmaceutical sector, and rising potential of glycomics in biomarker discovery. Increasing demand for personalized medicines to treat chronic diseases and rapid development personalized glycomedicine are also expected to contribute to revenue growth of this segment over the forecast period. Growing funding and financial support by government to accelerate glycomics and proteomics research and increasing expenditure on R&D are also expected to fuel revenue growth of the segment over the forecast period.
End-use Outlook:
Based on end-use, the global glycomics/glycobiology market has been segmented into academic & research institutes, CROs, and pharmaceutical & biotechnology companies. Academic & research institutes segment is expected to account for largest revenue share in the global market over the forecast period. Increasing glycomics research, rising application of glycomics in biomedical research, biochemistry, and immunology, and growing collaborations between research institutes and major pharmaceutical organizations are key factors expected to drive revenue growth of the segment over the forecast period. Pharmaceuticals and biotechnology companies segment is also expected to register considerable revenue growth over the forecast period owing to increasing investment in R&D sector for accelerating drug discovery and development and expanding scope of glycomics research.
Regional Outlook:
Based on regional analysis, North America accounted for largest revenue share in the global market in 2020 and is expected to account for a considerable revenue share over the forecast period. Growth can be attributed to robust presence of key companies in the region, increasing government funding for R&D activities, and rising research activities in the field of glycobiology. Increasing prevalence of chronic diseases and growing demand for personalized medicine have led to more drug research and development activities and this is expected to further boost revenue growth of the market in the region.
Asia Pacific is expected to register a rapid revenue CAGR over the forecast period owing to rapidly growing biopharmaceutical industry in the region and growing investment in CROs for development and production of drugs and biologics. Rapid technological advancements, increasing research in glycomics and access to new and innovative technologies are key factors driving revenue growth of the market in Europe.
Competitive Landscape:
Competitive landscape of the global glycomics/glycobiology market comprises key companies on a regional and global level. Key players are engaged in developing innovative and advanced products and solutions to cater to growing global demand and expand their product portfolio to gain a robust footing in the market. Collaborations, mergers and acquisitions, and partnerships are a crucial part in the market.
Major companies include Thermo Fisher Scientific, Inc. Merck KGaA, Agilent Technologies Bruker Corporation, New England Biolabs, Danaher, Shimadzu Corporation, Takara Bio, Inc., Asparia Glycomics S.L, and ProZyme.
Some notable developments in the market include:
- In April 2021, BridgeBio Pharma, Inc. and GlycoNet, which is a pan-Canadian Network of Centers of Excellence, announced a strategic collaboration to translate scientific research in glycomics to potential treatments for genetic disorders. BridgeBio will work in association with researchers from GlycoNet to select research programs that can be translated into treatments for genetic diseases.
- In December 2020, Griffith University’s Institute for Glycomics was awarded USD 2.66 Million by the National Health & Medical Research Council (NHMRC) under the Ideas Grant Funding to support four crucial research studies. The grant will be used for developing vaccines against bacteria, viruses, and bacterial toxins.
- In February 2020, CQDM and GlycoNet announced a strategic partnership aimed at supporting development of novel and innovative technologies in drug discovery and co-finance biopharmaceutical research projects in glycoscience across Canada.
Segments Covered in the Report:
This report offers historical data and forecasts revenue growth at a global, regional, and country level, and provides analysis of the market trends in each of the sub-segments from 2018 to 2030. For this study, Reports and Data has segmented the global glycomics/glycobiology market based on, product, application, end-use, and region:
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Glycomics/Glycobiology Market Report Scope
Segments covered By Product Outlook, Application Outlook, End-use Outlook, Regional Outlook
By Product Outlook
- Enzymes
- Glycosidases & Neuramidases
- Glycosyltransferases & Sialytransferases
- Others
- Instruments
- Mass Spectrometry Instruments
- Chromatography Instruments
- Arrays
- Others
- Kits
- Glycan Releasing Kits
- Glycan Labelling Kits
- Glycan Purification Kits
- Others
- Reagents
By Application Outlook
- Drug Discovery & Development
- Diagnostics
- Others
By End-use Outlook
- Academic Research Institutes
- Pharmaceutical and Biotechnology Companies
- CROs
- Others
Regional scope
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
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