KISS 1 is a metastasis-suppressor gene which helps to prevent the spread of cancers, including melanoma, pancreatic and ovarian cancers to name a few. But new research from Western University’s Schulich School of Medicine & Dentistry shows that kisspeptins -peptide products of KISS1, actually make some breast cancers worse, with a higher tumor grade and metastatic potential. The research is published online in the journal Endocrinology.