BioSpace News Archive

Drug Development

Merck KGaA’s BTK Inhibitor Fails Phase III Multiple Sclerosis Studies

In two late-stage trials, the experimental oral drug evobrutinib was unable to significantly reduce annualized relapse rates in MS patients compared with Sanofi’s Aubagio tablets.

December 6, 2023
·
2 min read
·
Tristan Manalac
Drug Development

Novo’s Wegovy Has Highest Adherence Rates in New Study of Weight-Loss Drugs

The study found only 19% of nearly 2,000 patients were still taking their prescribed anti-obesity medication at 12 months, compared to 40% that continued with Novo Nordisk’s Wegovy.

December 6, 2023
·
2 min read
·
Kate Goodwin
Policy

FDA Accepts Priority Review of BMS Opdivo, Chemo in Bladder Cancer Race

The regulator has accepted Bristol Myers Squibb’s Opdivo and the chemotherapy cisplatin for priority review in patients with unresectable metastatic urothelial carcinoma, as well as Merck and Seagen’s first-line combo.

December 6, 2023
·
2 min read
·
Tyler Patchen
Career Advice

Career Coach: When Should New Grads Begin Applying for Jobs?

Carina Clingman, founder of The Collaboratory Career Hub, answers questions about the ins and outs of finding, landing and succeeding in openings in biotech.

December 6, 2023
·
8 min read
·
Carina Clingman
Deals

GLP-1 and ADC rollercoasters pick up speed

This week we discuss ups and downs in the weight loss and ADC markets - including Altimmune, Pfizer setbacks, AbbVie’s ImmunoGen buy and more.

December 6, 2023
·
1 min read
FDA

Novartis Wins FDA Approval for Oral Monotherapy for Rare Blood Disorder

The Swiss pharma’s Fabhalta, a Factor B inhibitor, is the first FDA-approved oral monotherapy for adults with the rare blood disorder paroxysmal nocturnal hemoglobinuria.

December 6, 2023
·
2 min read
·
Tristan Manalac
Drug Development

Opinion: Leveraging tRNA to Scale Genetic Medicines for Rare Diseases and Beyond

Transfer RNA’s unique biology could enable a mutation-specific, gene-agnostic—and more cost effective—approach to developing treatments for thousands of rare and ultra-rare diseases.

December 6, 2023
·
5 min read
·
Michelle C. Werner
Policy

Sen. Bill Cassidy Eyes Legislation to Improve Access to Gene Therapies

With the biopharma industry’s looming wave of gene therapy submissions and potential approvals, the senior senator is laying the groundwork for a legislative initiative to improve access to these expensive treatments.

December 6, 2023
·
2 min read
·
Tristan Manalac
Career Advice

Recruiters Turn to Scientific Publications to Find Skilled Professionals

Although looking for candidates on platforms like LinkedIn continues to be the norm, some headhunters are also combing Google Scholar and PubMed for authors with relevant skills.

December 6, 2023
·
3 min read
·
Aayushi Pratap
Job Trends

Press Release: Sanofi Pipeline Transformation to Accelerate Growth Driven by Record Number of Potential Blockbuster Launches, Paving the Way to Industry Leadership in Immunology

Sanofi is hosting an Investor R&D Event in New York providing updates and insight into its innovative pipeline and new growth drivers.

December 6, 2023
·
8 min read