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Drug Delivery
Lilly Cuts Zepbound Prices, Again, When Buying Through DTC Program
Following Novo Nordisk’s price cuts for its own GLP-1 medicines, Eli Lilly is offering discounts for the obesity drug purchased through LillyDirect. Both pharmas recently struck a deal with the White House for cheaper prices via the yet-to-be-launched TrumpRx.
December 1, 2025
·
1 min read
·
Dan Samorodnitsky
Series B
Novartis-Backed Protego Eyes Pivotal Amyloidosis Study With $130M Series B
Protego Biopharma is advancing a small-molecule drug that helps light chain proteins fold correctly, in turn addressing the underlying biological cause of AL amyloidosis.
December 1, 2025
·
1 min read
·
Tristan Manalac
Gene editing
Regeneron Makes $275M Gene Editing Play With Tessera Partnership Targeting AATD
The centerpiece of the deal is the
in vivo
editor TSRA-196, which in preclinical studies has shown robust editing at SERPINA1, the locus linked to alpha-1 antitrypsin deficiency.
December 1, 2025
·
1 min read
·
Tristan Manalac
Vaccines
FDA’s Prasad Links 10 Child Deaths to COVID-19 Vaccines, Eyes Stricter Review Guidelines
The alleged deaths were detected by the FDA’s Vaccine Adverse Event Reporting System, reports from which “generally cannot be used to determine” causation or even contribution, according to the agency.
December 1, 2025
·
2 min read
·
Tristan Manalac
Layoff Tracker
Valneva Terminates 30 Amid Site Closure
Follow along as
BioSpace
tracks job cuts and restructuring initiatives.
December 1, 2025
·
92 min read
·
BioSpace Editorial Staff
FDA
FDA Delays Decision on Ascendis’ Dwarfism Drug By Three Months
If approved, Ascendis’ TransCon CNP would become the second therapy for achondroplasia, challenging BioMarin’s Voxzogo.
December 1, 2025
·
1 min read
·
Tristan Manalac
Press Releases
FDA Approves IsoPSA® -- Cleveland Diagnostics’ Novel Blood-Based Prostate Cancer Test
December 1, 2025
·
3 min read
Press Releases
Study Reveals Alarming Number of Invasive Breast Cancers in Younger Women
December 1, 2025
·
4 min read
PARTNERED WITH VIVA BIOTECH
Building the Next Generation of Biologics: Inside the Future of Protein Engineering
As bispecifics, ADCs, protein degraders, and AI-designed mini-proteins move into the clinic, discovery teams face a new bottleneck: engineering and producing molecules whose complexity challenges conventional workflows.
December 1, 2025
·
9 min read
·
BioSpace Insights
Press Releases
NRG Therapeutics Announces Further Expansion with the Appointment of Paul Thompson as Chief Development Officer
December 1, 2025
·
4 min read
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