Induced pluripotent stem cells have unlocked a new potential in regenerative medicine, as it overcomes the limitations of embryonic stem cells.
Induced pluripotent stem cells (iPSCs) have unlocked a new potential in regenerative medicine, as it overcomes the limitations of embryonic stem cells (ESCs). An emerging application area in the iPSCs market is drug discovery and development. Some of the diseases where they hold a vast potential are Parkinson’s disease, myocardial infarction, spinal cord trauma, and diabetes. Researchers consider silencing retroviruses in the human genome a key approach in disease management.
Over the past few years, patient-specific stem cells are used in drug development, in a bid to unveil personalized regenerative cell therapies. Biotech companies are aiming at safe reprogramming of cells, such as by adopting novel strategies in reprogramming of somatic cells to produce iPSCs. These also help in safety and efficacy of the prevailing stem cells therapies.
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Clinical-stage Programs for Generating iPSCs Rising in North America
Advances in reprogramming transcription factors have opened new revenue potential in iPSCs market. Growing role of pluripotent stem cells in human cell lines is stridently expanding the canvas for players in the market. The risk of genetic aberrations is a key concern. The advent of better methods for generating iPSCs is bellwether for growth in the iPSCs market. For instance, clinical-stage programs for generating iPSCs in spinal cord injuries are expanding the canvas for stakeholders. Biotech companies in the developed countries have in recent years ramped up their research activities in ensuring immune-matched pluripotent cells. This will play a key role in stem cell-based therapy.
Growing focus on personalized regenerative cell therapies among medical researchers and healthcare proponents in various countries have catalyzed their scope of induced pluripotent stem cells market. Advent of new methods to induce safe reprogramming of cells have helped biotechnology companies improve the clinical safety and efficacy of the prevailing stem cells therapies. The relentless pursuit of alternative source of cell types for regenerative therapies has led industry players and the research fraternity to pin hopes on iPSCs to generate potentially a wide range of human cell types with therapeutic potential. Advances pertaining to better utilizing of retrovirus and lentivirus as reprogramming transcription factors in recent years have expanded the avenue for players in the induced pluripotent stem cells market.
Developing economies in Asia Pacific are seeing rise in investments in stem cell-based therapies. Healthcare companies are supporting personalized regenerative cell therapies. Clinical difference between ESCs and iPSCs are getting wider. However, chromosomal instability and tumor expression are key challenges in achieving an effective reprogramming process. Over the years, emerging markets are seeing reprogramming of animal somatic cells. Particularly, the idea that these pluripotent stem cells can be made to form any cells in the body has galvanized companies to test their potential in human cell lines. Also, a few biotech companies have intensified their research efforts to improve the safety of and reduce the risk of genetic aberrations in their approved human cell lines. Recently, this has seen the form of collaborative efforts among them.
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