According to the most recent analysis by Emergen Research, the worldwide in-situ hybridization market had a value of USD 14.32 billion in 2021 and is projected to grow at a rate of 8.14% during the forecast period.
According to the most recent analysis by Emergen Research, the worldwide in-situ hybridization market had a value of USD 14.32 billion in 2021 and is projected to grow at a rate of 8.14% during the forecast period. Growing incidence of infectious diseases, genetic abnormalities, and cancer is a significant factor influencing market revenue growth.
Globally, there has been an increase in the prevalence of cancer over time. Recurrent genetic aberrations have been identified as probable initiators of a range of cancers in extensive investigations on human diseases undertaken over the last two decades. IHC and DNA FISH are integrated by cytogenetic tests like ISH, completing the in situ toolkit for researchers to find, create, and use next-generation diagnostic techniques. The interaction between cancer cells and the tumour microenvironment as the cancer progresses can be better understood with direct imaging of gene expression in situ at the RNA level.
GLOBOCAN estimates that in 2018, cancer killed 9.6 million people and afflicted 43.8 million people. Cancer is responsible for about one out of every six fatalities worldwide. In 2018, there were also 18.1 million new cases. With a death rate of 16.5 million in 2040, the incidence of cancer might rise to 29.5 million people.
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The frequency of haemophilia has tripled to reach 1,125,000 among genetic illnesses, according to study from McMaster University (Canada), compared to earlier estimates of 400,000. Canada, France, Italy, the United Kingdom, Australia, and New Zealand are the nations most severely impacted. The market for in situ hybridization is probably going to be affected by this increase.
Several academic institutions and organisations have engaged in extensive R&D over the past few years to create a system that can analyse the molecular profiles of individual cells. For instance, Proximity Ligation in situ Hybridization, an in situ hybridization method created by Bio-protocol. The method is praised for its great performance, affordability, quick multiplexing, and ease of use.
The accessible in situ hybridization technique makes it easier for developing nations—which are more vulnerable to infections and diseases—to use. To raise public awareness, regulatory organisations have introduced a number of policies and programmes. For instance, to raise awareness of infectious diseases, the WHO and the Federal Capital Territory Public Health Department of Nigeria cooperated in August 2021.
The utilisation of ISH goods has increased recently, which has resulted in an increase in the quantity of specialist contract research companies. This made the market competition more fierce. For instance, Reveal Biosciences provides sophisticated tissue technology services and tissue research employing in situ hybridization and other techniques while adhering to strict legal constraints and high sample throughput.
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Some Key Highlights From the Report
- Some major companies in the global market report include Thermo Fisher Scientific Inc., Merck KGaA, Biocare Medical, LLC., Abbott Laboratories, Agilent Technologies Inc., F. Hoffmann-La Roche Ltd., Zytomed Systems GmbH, Gerresheimer AG, Genomed Biotechnologies, Inc., and Abnova Corporation.
- OnCORE Pro, a fully automated In-Vitro Diagnostic (IVD) Benchtop platform for Immunohistochemistry (IHC) and In-Situ Hybridization (ISH) applications, was introduced by BioCare Medical on January 4th, 2021. Due to the device's ability to perform both fluorescence and chromogenic ISH, a wide range of industrial and academic applications are now possible. With the aid of high-throughput slide processing, ONCORE Pro can run 36 slides at once, each of which can be subjected to a different procedure. This release is anticipated to make it possible for both big and little diagnostic facilities, research labs, and other end users to do IHC, FISH, and CISH on a benchtop scale while maximising sample processing turnaround time.
- Based on technique, the FISH segment controlled the in situ hybridization market, accounting for 53.9% of total revenue in 2020. This can be ascribed to the numerous applications, such as the ability to diagnose congenital illnesses like Down syndrome and Edwards syndrome. The use of FISH technology has expanded as a result of the expanding prevalence and diagnosis of these disorders, which is anticipated to hasten market expansion.
- Due to its advantages over FISH in terms of cost, dependability, and practicality, the CISH market segment has also amassed a sizeable portion of in situ hybridization over time. With the help of the technology, traditional peroxidase reactions can detect copies of the HER-2/neu oncogene. The ISH market is expected to develop at a faster rate than average over the course of the forecast period due to the acceptance of CISH technology for HPV genotyping on cervical smears.
- In situ hybridization was dominated by the DNA probe segment, which in 2020 accounted for 51.1% of total revenue. Due to the creation of novel diagnostic assays and instruments for examining DNA and RNA molecules based on nucleic acids, the RNA probe showed a greater growth rate during the anticipated time.
- With a revenue share of 36.3% in 2020, the instruments sector dominated the market for in situ hybridization. The expansion of diagnostic and research laboratory chains is the cause of the rising demand for instruments. The expansion of in situ hybridization is also projected to be boosted by an increase in the number of strategic activities among the companies to broaden their product portfolio.
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Emergen Research has segmented the global in-situ hybridization market based on technology, product, application, end-use, and region:
- Technology Outlook (Revenue, USD Billion; 2019-2030)
- Fluorescence In-Situ Hybridization (FISH)
- Chromogenic In-Situ Hybridization (CISH)
- Product Outlook (Revenue, USD Billion; 2019-2030)
- Kits and Reagents
- Probes
- Instruments
- Software
- Others
- Application Outlook (Revenue, USD Billion; 2019-2030)
- Cancer Diagnosis
- Disease Diagnosis
- Immunology
- Neuroscience
- Cytology
- Others
- End-Use Outlook (Revenue, USD Billion; 2019-2030)
- Hospitals
- Diagnostic Centers
- Pharmaceutical Industry
- Academic and Research Laboratories
- Biotechnology Industry
- Contract Research Organizations (CRO)
- Regional Outlook (Revenue, USD Billion; 2019-2030)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Benelux
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- UAE
- South Africa
- Turkey
- Rest of Middle East & Africa
- North America
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