The global epigenetics market size was USD 9,143.1 Million in 2020 and is expected to reach a value of USD 36.52 Billion by 2030, and register a CAGR of 18.8% during the forecast period.
The global epigenetics market size was USD 9,143.1 Million in 2020 and is expected to reach a value of USD 36.52 Billion by 2030, and register a CAGR of 18.8% during the forecast period. Rising prevalence of various types of cancer and other chronic diseases, growing global geriatric population, and need for advanced treatment and pharmaceuticals are major factors expected to drive market growth. There has been a significant increase in the number of people suffering from cancer across the globe. According to WHO, the number of people suffering from cancer is expected to increase from 14.1 Million in 2012 to 19.3 Million by 2025
Market Dynamics Drivers:
Epigenetic changes such as dysregulation of DNA methylation are associated with cancer development and progression. Epigenetics provides new opportunities for deriving therapeutic strategies designed to reverse dysregulation in cancer. Various cancer research studies that utilize epigenetics technique are currently underway; significant investments are being made to support these studies. For instance, in February 2016, the University of Southampton and University Hospitals Southampton NHS Foundation Trust (UK) received USD 1.57 Million for genetics and genomics research related to cancer and infectious diseases. Similarly, in March 2015, Barts Cancer Institute’s Centre for Haemato-Oncology (UK) received funds worth USD 113.9 Million from the Medical Research Council to study epigenetic changes in cancer.
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Increasing investments for research on epigenetics to develop novel remedies in order to prevent and treat cancer by healthcare organizations including IHEC (International Human Epigenome Consortium), NCI (National Cancer Institute) and NIH (National Institute of Health) is expected to boost demand for epigenetics and drive market growth. For instance, NIH is funding epigenetics research via epigenomics program that has been started to actively support epigenetic research at a global scale. Increasing need to understand modifications of epigenetics at a molecular level for developing therapeutic solutions is expected to encourage healthcare organizations to invest in research and development activities. In addition, The EGRP (Epidemiology and Genomics Research Program) supports research activities to gain information and understand determinants of cancer occurrence and related outcomes.
Restraints:
High cost of instruments required for epigenetics research, as these are well-equipped with technologically advanced features and functionalities, and high cost of maintenance and various indirect expenses are factors that could hamper revenue growth of the global epigenetics market to some extent. In addition, high investments required for required for procuring high-cost genomic instruments for research, and limited budget available with pharmaceutical companies and academic research laboratories are factors restraining further research activities by these sectors.
Product Outlook:
Among the product segments, the reagents accounted for the largest revenue share in the global epigenetics market in 2020. Histone and DNA modifiers are the major types of reagents used for epigenetics. Some of the common epigenetic reagents are antibodies, PCR reagents, histones, primers, electrophoresis reagents, nucleic acid analysis reagents, and buffers.
The kits segment is expected to register the highest revenue growth rate during the forecast period. Ready to use kits are manufactured by various biotechnology companies which are used for detecting epigenetic modifications. Kits available in the market include those designed for analysis of DNA methylation status, nucleic acid purification, and detection of histone modifications by various enzymes, and kits for chromatin immunoprecipitation, among others. Epigenetic diagnostic kits are used for diagnosis of disorders due to epigenetic modifications in the early stages and during treatment to check the efficacy of therapeutics.
Technology Outlook:
Among the technology segments, the DNA methylation segment accounted for the largest revenue share of 36.3% in 2020. DNA methylation is the covalent addition of a methyl group in the cytosine ring, which leads to inhibition of transcription.
The histone acetylation segment is expected to register the highest revenue growth rate during the forecast period, owing to its enhanced efficacy due to development of novel mechanisms. It refers to as enzymatic incorporation of an acetyl group to lysine residues. Histone acetylation is involved in controlling cellular processes such as gene silencing, chromatin transcription and dynamics, progression of cell cycle, differentiation, apoptosis, DNA replication, neuronal repression, nuclear import, and DNA repair.
Application Outlook:
Among the application segments, the oncology segment accounted for the largest revenue share in the global epigenetics market in 2020. Increasing prevalence of various types of cancer globally, along with rising cases of deaths due to cancer disease are factors driving revenue growth of this segment. Moreover, research and development of new products and potential products in the pipeline is supporting revenue growth of this segment.
The non-oncology segment is expected to register the highest revenue growth rate during the forecast period. This can be attributed to constant research and development initiatives undertaken by private institutions and biopharmaceutical companies for identification of epigenetic markers related to these disorders as well as for detection of biomarkers for drug development. Epigenetic modifications are being proved to be the base of various non-oncology disorders such as metabolic disorders, neurodegenerative disorders, and infectious diseases.
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Region Outlook:
North America market accounted for the largest revenue share in the global epigenetics market in 2020. Governments of the countries in the region are encouraging ongoing research activities on epigenetics by providing funds which is a major factor driving North America market growth. In addition, presence of advanced healthcare facilities and constant advancements in diagnostic procedures are other major factors supporting market growth in the region. In addition, the common fund supported programs in the U.S. are anticipated to support epigenetic research activities, covering a varied range of diseases including oncology and non-oncology diseases such as cardiovascular, metabolic, inflammatory, and other diseases.
The Asia Pacific market size was USD 2,011.5 Million in 2020, and revenue growth of the Asia Pacific market is expected to expand at a significantly high rate during the forecast period. This is due to increasing medical tourism resulting in high demand for advanced treatments, however limited budgets could restrain growth of the market in the region to some extent.
Companies considered and profiled in the market report
Some of the prominent players in the market include Illumina (U.S.), Thermo Fisher Scientific (U.S.), Merck Millipore (U.S.), Abcam (U.K.), Active Motif (U.S.), Bio-Rad Laboratories (U.S.), New England Biolabs (U.S.), Agilent (U.S.), QIAGEN (Netherlands), Zymo Research (U.S.), PerkinElmer (U.S.), and Diagenode (Belgium). The market players have adopted various strategies including mergers, acquisitions, partnerships, and new product developments, among other strategies, to stay ahead of the competition and expand market footprint.
Segments covered in the report:
This report offers historical data points and forecasts and revenue growth at a global, regional, and country level, and provides analysis, industry trends, and consumption pattern details for each segment from 2018 to 2030. The global epigenetics market report includes market size, market share, ongoing industry trends, market revenue or revenue share contributed by each regional market, and each of the segments. In addition, the report offers industry analysis in terms of revenue growth opportunities for existing as well as entry level players.
The report includes a detailed view of the global epigenetics market, along with changing dynamics and trends, scenarios, recalls, detailed market and regional segmentation, regional landscape, analysis and evaluation or revenues and investments, and details of historical, current, and projected revenue. Also, recent trends, DROT, and related developments in the global epigenetics market are included. Competitive landscape includes revenue share, financials, and various strategies adopted by key players in the market along with product offerings.
For the purpose of this report, Reports and Data has segmented the global epigenetics market on the basis of product, technology, application, end use, and region:
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Epigenetics Market Report Scope
Segments covered By Product Outlook, Technology Outlook, Application Outlook, End Use Outlook, Regional Outlook
By Product Outlook
Reagents
Kits
Chip sequencing kit
Whole Genomic Amplification kit
Bisulfite Conversion kit
RNA sequencing kit
Others
Instruments
Enzymes
Services
By Technology Outlook
DNA Methylation
Histone Methylation
Histone Acetylation
Large non - coding RNA
MicroRNA modification
Chromatin structures
By Application Outlook
Oncology
Solid tumors
Liquid tumors
Non - oncology
Inflammatory diseases
Metabolic diseases
Infectious diseases
Cardiovascular diseases
Others
By End Use Outlook
Academic and Research Institutes
Pharmaceutical and Biotechnology Companies
Contract Research Organizations (CROs)
Regional scope
North America
Europe
Asia Pacific
Latin America
Middle East & Africa
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