Tr1X

ABOUT

Tr1X is a private, clinical-stage biotechnology company focused on developing a novel class of regulatory T cell-based products to cure autoimmune and inflammatory diseases and transform patient lives. Founded by industry experts, including the scientists who discovered Type 1 regulatory T (Tr1) cells, the company is developing a pipeline of off-the-shelf allogeneic cell therapies to treat and potentially cure autoimmune diseases with high unmet medical need. Our novel regulatory T cell-based therapeutics are designed to mimic the function of naturally occurring Tr1 cells, an important subset of regulatory cells, which work to restore immune tolerance, stopping severe autoimmune and inflammatory diseases in their tracks. Tr1X is the first company ever to use an allogeneic engineered Tr1 cell therapy in clinical trials. Tr1X is headquartered in San Diego, CA. For more information, please visit www.tr1x.bio.

4242 Campus Point Court, Suite 500, San Diego, CA 92121
FEATURED NEWS
Tr1X Plans to Initiate a Phase 1/2a study and Dose the First Patient by the End of 2024
TRX103 is designed to reset the immune system, improve clinical outcomes, and potentially cure patients suffering from autoimmune and inflammatory disorders This marks the first use of an allogeneic engineered Type 1 Treg (Tr1) cell therapy in clinical trials. The first patient has successfully cleared the safety period with no serious adverse events. Additional preliminary safety and effectiveness data readouts expected by Q4 2024.
Tr1X, Inc. today announced the U.S. Food and Drug Administration (FDA) accepted the company’s Investigational New Drug (IND) application for TRX103 for the prevention of Graft versus Host Disease (GvHD) in patients undergoing HLA-mismatched hematopoietic stem cell transplantation (HSCT).
NEWS
The San Diego-based startup, specializing in allogeneic engineered Treg and CAR-Treg cell therapies, plans to be in Phase I clinical trials in multiple indications in 2024.
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