BioSpace News Archive

Experic

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GLP-1

Pfizer Cautiously Optimistic on Obesity Pill as Kailera Challenges Lilly’s Zepbound With Strong Phase II Data

Obesity continues to grab attention at the J.P. Morgan Healthcare Conference in San Francisco, with both Pfizer and Kailera Therapeutics outlining their plans in the space moving forward.

January 14, 2025

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2 min read

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Tristan Manalac

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Cancer

Where Keytruda Failed, Regeneron Touts Phase III Skin Cancer Win for Libtayo

The positive trial results could help Regeneron cushion the blow of its disappointing fourth-quarter sales for Eylea, which exceeded the consensus by a modest 1% and are bogged down by the slow conversion of patients to the high-dose formulation.

January 14, 2025

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2 min read

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Tristan Manalac

The Gariep Dam overflowing. The dam is the largest in South Africa. It is in the Orange River on the border between the Free State and Eastern Cape Provinces. Monochrome

Deals

Biopharma Deals Start Flowing at JPM25—With One Dwarfing Last Year’s Activity

J.P. Morgan kicked off with a flurry of deals, with Eli Lilly, GSK and Gilead all announcing deals potentially worth more than $1 billion while J&J committed $14.6 billion to buy Intra-Cellular. These moves have reinvigorated sentiment across the biopharma industry.

January 14, 2025

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3 min read

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Annalee Armstrong

Earnings

Sarepta Previews Q4 Findings, Touts Elevidys Earnings Beat

Sarepta Therapeutics’ Duchenne muscular dystrophy therapy Elevidys handily beat analysts’ expectations in the fourth quarter of 2024, reflecting the biotech’s “world-class” execution, according to BMO Capital Markets analysts.

January 14, 2025

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2 min read

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Tristan Manalac

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Gene therapy

Regenxbio Jumps on Potential $800M Rare Disease Deal With Nippon Shinyaku

In exchange for its investigational gene therapies, Regenxbio will receive $110 million upfront and up to $700 million in milestones. After hitting an all-time low of $6.95 at close of business yesterday, the stock surged on the news by nearly 20% before markets opened Tuesday.

January 14, 2025

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2 min read

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Tristan Manalac

Drug Development

Could New Leqembi Formulations Boost Lagging Sales in Alzheimer’s?

The FDA accepted Biogen and Eisai’s BLA for a subcutaneous administration of the anti-amyloid antibody Monday as the partners await the regulator’s decision on a new intravenous regimen following an underwhelming launch riddled with coverage and accessibility barriers.

January 14, 2025

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1 min read

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Kate Goodwin

Earnings

Lilly Projects 2024 Revenue Miss as Zepbound, Mounjaro Disappoint

The updated guidance, which was largely driven by lower-than-anticipated sales of GLP-1 blockbusters Mounjaro and Zepbound, sent Eli Lilly’s shares cratering by as much as 8% Tuesday, even as the company forecasted robust 2025 revenue.

January 14, 2025

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2 min read

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Dan Samorodnitsky