BioSpace News Archive

Drug Development

Bristol-Myers Squibb’s Opdivo Fails to Show Superiority to Bayer’s Nexavar in Liver Cancer

The drug failed to meet statistical significance for overall survival. However, the company is putting a positive spin on it, saying it showed a clear improvement trend in OS for patients treated with Opdivo compared to sorafenib.

June 24, 2019
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2 min read
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Mark Terry
Drug Development

MyoKardia Publishes Data in Nature Digital Medicine Showing Potential of Wrist-Worn Biosensor to Screen for Hypertrophic Cardiomyopathy

Continuous Monitoring with Wearable Device Detected Distinct Pulse Wave Patterns in Obstructive Hypertrophic Cardiomyopathy Patients as Compared to Healthy Volunteers

June 24, 2019
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5 min read
Deals

Bristol-Myers Squibb Plans to Sell Celgene’s Otezla in Attempt to Expedite Acquisition

“Bristol-Myers Squibb is committed to working with regulatory authorities around the world on the proposed combination with Celgene,” the company stated. “The company is focused on realizing the promise of the transaction, and is continuing to work to complete the transaction on a timely basis.”

June 24, 2019
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2 min read
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Mark Terry
Policy

Glenmark Works to Address Concerns in FDA’s CRL and Gain Approval for Ryaltris

Glenmark said it should be able to resolve the FDA’s concerns within six to nine weeks and will work with the regulatory agency toward approval.

June 24, 2019
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2 min read
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Alex Keown
Drug Development

AbbVie Resumes Multiple Myeloma Trial After FDA Lifts Partial Hold

The partial clinical hold was lifted after the company revised the study protocol for the trial. The partial clinical hold remains on other multiple myeloma trials involving venetoclax.

June 24, 2019
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3 min read
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Alex Keown
Pharm Country

New BTX 1801 data presented at ASM Microbe 2019

Botanix collaborator Dr Mark Blaskovich of the University of Queensland presented new antimicrobial data at ASM Microbe 2019, highlighting cannabidiol as a remarkably active Gram-Positive antibiotic

June 24, 2019
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3 min read
Expedeon AG introduces Lightning-Link® Metal Labelling Kits to support single cell analysis

Novel antibody labelling immunoassay technology for multiplex immune profiling addresses one of the fastest growing, billion-dollar life science market sectors

June 24, 2019
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4 min read
Deals

Domain Therapeutics strengthens its scientific advisory board with leading GPCR and disease experts

Domain Therapeutics announces the appointment of world-renowned GPCR and drug discovery and development experts to its Scientific Advisory Board (SAB): Pr. Silvio Gutkind, Pr. Morley Hollenberg and Pr. Brigitte Kieffer.

June 24, 2019
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5 min read
Deals

Medtronic Announces Cash Tender Offers for up to $4.175 Billion of Outstanding Debt Securities Issued by Medtronic, Inc., Medtronic Global Holdings S.C.A. and Covidien International Finance S.A.

Medtronic plc announced the commencement of two cash tender offers by its wholly-owned indirect subsidiaries, Medtronic, Inc., Medtronic Global Holdings S.C.A. and Covidien International Finance S.A. (“CIFSA” and, together with Medtronic, Inc.

June 24, 2019
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13 min read
LDL-Cholesterol Does Not Predict Heart Risk Among Heart Patients

New Diagnostic Test, CERT, Improves Risk Prediction Over Standard Laboratory Tests

June 24, 2019
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3 min read