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Cardiovascular disease
Cytokinetics’ Moment of Truth: Can Aficamten Take On BMS in Hypertrophic Cardiomyopathy?
After 27 years in business, Cytokinetics hopes to pit its own cardiac myosin inhibitor against one it initially developed—now owned by Bristol Myers Squibb—in a market worth billions. Aficamten has a PDUFA date of Dec. 26.
December 19, 2025
·
5 min read
·
Dan Samorodnitsky
Infectious disease
Insmed Delivers ‘Rare Disappointment’ as Brinsupri Flops in Mid-Stage Rhinosinusitis Study
Insmed pointed to a strong placebo response as the reason for the trial’s failure.
December 19, 2025
·
2 min read
·
Tristan Manalac
ADCs
Patient Deaths Put Merck, Daiichi Sankyo’s Antibody-Drug Conjugate on Hold
The fatalities were attributed to interstitial lung disease, a known side effect of Daiichi Sankyo’s DXd-based antibody-drug conjugates. A spokesperson declined to say how many patients died.
December 19, 2025
·
2 min read
·
Tristan Manalac
Immunology and inflammation
Takeda’s $4B Nimbus Bet Pays Off With ‘Best-in-Class’ Phase III Plaque Psoriasis Data
With zasocitinib, Takeda is looking to challenge Bristol Myers Squibb’s kinase inhibitor Sotyktu, for which the Japanese pharma is running a head-to-head study in plaque psoriasis. Takeda expects to file for zasocitinib’s FDA approval next year.
December 19, 2025
·
2 min read
·
Tristan Manalac
Press Releases
MEDIPOST Announces the Exclusive Commercialization License Agreement with Teikoku Seiyaku for Knee Osteoarthritis Treatment CARTISTEM® in Japan
December 19, 2025
·
3 min read
Press Releases
IBA acquires ORA expanding its strategic leadership in Nuclear Medicine
December 19, 2025
·
3 min read
Press Releases
Ipsen update on Phase II FALKON trial in patients with ultra-rare bone disease, fibrodysplasia ossificans progressiva (FOP)
December 19, 2025
·
7 min read
Press Releases
Vicore Pharma To Move To The Nasdaq Stockholm Mid Cap Segment
December 19, 2025
·
1 min read
Press Releases
Guerbet: Appointment of Mr. François Convenant as Senior Vice President of Interventional Radiology and his entry into the Executive Committee
December 19, 2025
·
2 min read
Press Releases
Genenta Science Provides Update on CEO Ownership
December 19, 2025
·
3 min read
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