Modex Therapeutics

ModeX Therapeutics, an OPKO Health company, is the leading clinical-stage biopharmaceutical company developing unique and proprietary multispecific therapeutics. Its MSTAR platform unites the power of multiple biologics in a single molecule to create multispecific antibodies that bind four or more targets with unprecedented versatility and potency for complex diseases. Its promising first-in-class immunology pipeline includes candidates against immune diseases, including cancer (both solid and hematologic tumors), immune impairment, as well as several of the world’s most pressing viral threats. Our founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients.

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Leadership
  • ModeX Therapeutics, Co-Founder Opko Health, President and Vice Chairman of the Board of Directors
    Elias Zerhouni
    ModeX Therapeutics, Co-Founder

    Opko Health, President and Vice Chairman of the Board of Directors
  • Gary Nabel
    ModeX Therapeutics, Co-Founder, President and CEO

    Opko Health, Chief Innovation Officer and Board Director
  • John Mascola
    Chief Scientific Officer
  • Giovanni Abbadessa
    Chief Medical Officer
  • Kerry Culm
    Chief Development Officer
  • Ji Zhang
    Chief Operating Officer
20 Riverside Road
Weston, MA 02493
  • Featured Employer
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Our team is defined by transformative innovation and inspired by patients.
Multispecific biologics represent the future of medicine. Many untreatable diseases arise from aberrations in multiple pathways, yet most medicines only act on single targets. With our multispecific antibody platform, MSTAR, we can reliably and rapidly generate candidates that target up to six distinct biological pathways in a single molecule for the first time. This dramatically expands the therapeutic potential of antibodies.
We are driven by
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We believe that the true measure of an innovation’s impact is the number of patients it helps. A drive to work on the most complex scientific challenges of our time is necessary but not sufficient by itself—creative thinking is what will separate us from everyone else. We are a project-focused group committed to fostering a culture where a wide variety of perspectives are valued. We’re ambitious, but we have fun working together and know the best science is a product of creative collaboration.

Ready to break new ground with us?
We are a project-focused group committed to fostering a culture where a wide variety of perspectives are valued. We’re ambitious, but we have fun working together and know the best science is a product of creative collaboration.

We are shaping a new and better way to make transformational medicines a reality for people in need.
  • “It’s the people within ModeX that make it special. The leadership team is second to none in terms of scientific accolades and business acumen -that’s why I joined, because I knew we have a real chance to make breakthrough therapies here. We have terrific scientists that are all working to make ModeX a potential shooting star in the medical world.”
    Ed Seung, Principal Scientist
  • “ModeX - from senior leaders to young bench scientists - has fostered a collaborative and science-first working culture that really motivates and challenges us to do our best every day.”
    Hao Chen, Director, Protein Sciences
  • My position at ModeX is my first job after receiving my doctorate, and I could not have asked for a better experience. The location, the people, and the science each speaks for itself. It’s a privilege and a career-defining opportunity to be on such an ambitious and sophisticated team rapidly advancing promising therapies towards the clinic.”
    Mark Greci, Scientist
NEWS
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