Codagenix, Inc.
3 Bioscience Park Dr.
Suite 503
Farmingdale
NY
11735
United States
Website: http://codagenix.com/
Email: info@codagenix.com
About Codagenix, Inc.
Codagenix is a clinical stage, venture and public-sector-funded small business that is using our synthetic biology-based vaccine design platform “SAVE” to construct prophylactic viral vaccines and oncolytic agents. All viruses, whether Zika or influenza, uses the host cell ribosome to translate their genome and synthesize their proteins. SAVE is a computer algorithm that re-codes and “de-optimizes” viral genes – in turn putting the wild-type viral genes in a “language” read slowly by the mammalian host ribosome. De-optimization results in a vast reduction of pathogenesis, yet induction of a potent immune response given the presentation of ALL, perfectly matched antigens of the target. This platform has universal applications to the re-design of viral genomes.
Codagenix’s lead program is a live-attenuated, universal Influenza vaccine that has demonstrated safety and broad immunogenicity in a Phase I clinical trial. Using SAVE, Codagenix is developing a pipeline of live-attenuated vaccines against other targets including: RSV (Phase I Q1-2019), Zika (Phase I Q1-2019), and Dengue as well as rationally designed oncolytic candidates against Melanoma, Triple-Negative Breast Cancer, and Neuroblastoma.
Codagenix also has an established partnership in the agricultural space - designing and co-developing SAVE-deoptimized vaccines for swine, canine, bovine, and other markets.
22 articles with Codagenix, Inc.
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Codagenix Intranasal COVID-19 Vaccine Shows Potent Cellular Immune Response Against Conserved Viral Proteins, Indicating Potential for Immunogenicity Against Omicron and Future Variants in Phase 1 Data
3/17/2022
Codagenix Inc. today announced interim Phase 1 data indicating induction of T cell immunity against highly-conserved antigens of the SARS-CoV-2 Omicron variant following two doses of its intranasal vaccine, CoviLiv (previously called Covi-Vac).
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Codagenix is entering the vaccine arena with a possible new frontrunner in protection: CoviLiv. It's an intranasal COVID vaccine that provides hope against subvariants.
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BioSpace Movers & Shakers, Jan. 14
1/14/2022
Biopharma and life sciences companies strengthen their leadership teams and boards with these Movers & Shakers. -
Codagenix Welcomes Bruce Taillon as Executive Vice President of Animal Health
1/12/2022
Codagenix, Inc. today announced the appointment of Bruce E. Taillon, Ph.D., as Executive Vice President of Animal Health.
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Codagenix to Present Promising Preclinical Data for Oncolytic Virus Therapeutic CodaLytic™ at the 2021 Society for Immunotherapy of Cancer (SITC) Annual Meeting
11/9/2021
Codagenix, Inc., a clinical-stage synthetic biology company pioneering a novel platform for vaccines and oncolytic virus therapies, today announced they will present data indicating preclinical efficacy of CodaLytic™, its first rationally attenuated oncolytic virus immunotherapy, at the Society for Immunotherapy of Cancer (SITC) 36th Annual Meeting.
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Codagenix Announces Appointment of Two New Members to its Board of Directors
10/6/2021
Codagenix, Inc. this week announced the appointment of two new members to its Board of Directors each with significant biotechnology and life sciences experience, Lori Rudolph-Owen , Ph.D., and Jill Howe .
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Codagenix Presents Positive Phase 1 Data for COVI-VAC Intranasal COVID-19 Vaccine at IDWeek 2021
9/29/2021
Codagenix, Inc., a clinical-stage biotechnology company pioneering a novel platform for vaccines and oncolytic virus therapies, today presented data from ongoing studies of their novel intranasal COVID-19 vaccine, COVI-VAC, at the IDWeek 2021 annual conference held virtually September 29-October 3.
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Codagenix Announces Safety and Immunogenicity Data from Phase 1 COVID-19 Intranasal Vaccine Trial and Intent to Progress to Phase 2/3 Studies
9/22/2021
Codagenix Inc. today announced that their novel intranasal COVI-VAC vaccine has demonstrated promising safety and immunogenicity results in their Phase 1 dose escalation trial in healthy adults.
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Codagenix Appoints Tyler Cook as Chief Financial Officer
8/26/2021
Codagenix Inc. today announced the appointment of Tyler Cook as Chief Financial Officer (CFO).
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Intranasal COVID-19 vaccine demonstrates single-dose efficacy in preclinical studies, in parallel with achievement of Phase 1 clinical milestone
6/30/2021
Codagenix Inc., a clinical-stage synthetic biology company pioneering a novel platform for vaccines and oncolytic virus therapies, today announced preclinical data published in the Proceedings of the National Academy of Science (PNAS) supporting the potential safety and efficacy of COVI-VAC, the company's intranasal live-attenuated COVID-19 vaccine
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Codagenix Appoints Johanna Kaufmann, Ph.D., Executive Vice President, Oncology to Lead Customization of Oncolytic Viruses for Solid Tumors
5/4/2021
Codagenix Inc., a clinical-stage biotechnology company developing prophylactic vaccines and oncolytic virus therapies for cancer, today announced the appointment of innovative oncology leader Johanna Kaufmann, Ph.D., as Executive Vice President, Oncology.
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Codagenix Appoints Linda Maldonado as VP, Biologics Chemistry and Manufacturing Controls
4/14/2021
Ms. Maldonado to Oversee Manufacturing Development of Codagenix's Vaccines as Clinical Trials for COVID-19, RSV and Flu Progress
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With billions invested in R&D over the past year to find vaccines and therapies for the novel coronavirus, a few select life sciences companies and academic institutions are working on the hypothesis that intranasal vaccines and therapies could be key to stopping COVID-19 in its tracks, and provi...
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Codagenix's CEO to Present Update on COVI-VAC During New York Academy of Sciences Event, "Quest for a COVID-19 Vaccine"
2/1/2021
Codagenix Inc., a clinical-stage biotechnology company developing prophylactic vaccines and oncolytic virus therapies, announced that CEO J. Robert Coleman, Ph.D., M.B.A., will present an update on COVI-VAC during the New York Academy of Science's (NYAS) two-day webinar event, "Quest for a COVID-19 Vaccine,
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Codagenix Secures U.S. Patent for Codon-Deoptimized RSV Vaccine Candidates
1/26/2021
Codagenix Inc., a clinical-stage biotechnology company developing prophylactic vaccines and oncolytic virus therapies, announced the issuance of a patent for a vaccine focused on human codon-deoptimized respiratory syncytial viruses vaccine.
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Codagenix Inc. Completes Dosing for Phase 1 Trial of Live-Attenuated, Intranasal Vaccine for Respiratory Syncytial Virus (RSV)
12/1/2020
Codagenix Inc., a clinical-stage biotechnology company developing prophylactic vaccines and oncolytic virus therapies, announced today the completion of dosing in a Phase 1 clinical trial of its live attenuated CodaVax™-RSV vaccine, an intranasally-administered vaccine for the prevention of respiratory syncytial virus (RSV).
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Codagenix, Inc. Appoints Jeffrey Fu, Ph.D., Chief Business Officer
10/28/2020
Former Merck Executive and Vaccine Industry Leader to Drive Development Opportunities for Codagenix's Diverse Pipeline, Including Vaccine Candidates for SARS-CoV-2 and RSV
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Serum Institute of India Initiates Manufacturing of Codagenix's Intranasal Live-Attenuated COVID-19 Vaccine Candidate
9/22/2020
- Phase 1 clinical trial of CDX-005 expected to initiate prior to year-end 2020 - Serum Institute to ramp-up manufacturing for large-scale safety and efficacy studies and to meet global vaccine supply requirements [22-September-2020] FARMINGDALE, N.Y. , Sept. 22, 2020 /PRNewswire/ -- Codagenix, Inc., a clinical-stage biotechnology company developing pr
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The 11-person team at Codagenix may be tiny, but it has big plans for the company’s new COVID-19 vaccine.
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Codagenix Announces the Synthesis and Preliminary Safety of Scalable, Live-attenuated Vaccine Candidate Against COVID-19
6/18/2020
Codagenix, Inc., a clinical-stage biotechnology company developing prophylactic vaccines and oncolytic virus therapies, today announced the successful synthesis of a readily-scalable live-attenuated vaccine candidate against COVID-19. The vaccine, CDX-005, is currently undergoing safety and efficacy studies in animals and appears m