BioSpace News Archive

March 19, 2025

War-torn city vector illustration: depicts structures heavily damaged post aerial bombing or missile attacks during warfare.

Opinion

The Consequences of War for Drug Development and Delivery

The ongoing conflicts between Ukraine and Russia, as well as Israel and Palestine, have sent ripples across various industries, including pharma. Medical science liaisons can help.

March 19, 2025

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5 min read

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William Soliman

A businessman jumps over a cliff. Art collage.

Patents

Just How Steep Is the Drug Patent Cliff? Ask These Pharmas

With Keytruda, the best-selling drug in the world, facing the end of exclusivity in 2028, BioSpace looks at five drugs that have taken the leap off the patent cliff.

March 19, 2025

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5 min read

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Dan Samorodnitsky

Illustration silhouette people walking toward the destination of light with white line on yellow and blue empty background.

GLP-1

GLP-1 Drug Boom Recalls the Rise of PD-1 Checkpoint Inhibitors

The explosion of GLP-1 weight loss drugs is reminiscent of the early days of PD-1 inhibitors, but key market differences suggest history may not repeat itself.

March 19, 2025

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8 min read

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Ben Hargreaves

Collage showing one hand holding question mark and another hand holding a light bulb

Career Advice

Survivor Syndrome: 3 Steps for Keeping Your Career on Track After Layoffs

Layoffs leave more than empty desks—they leave uncertainty, guilt and anxiety. Three simple steps will help you regain control of your work, well-being and career.

March 19, 2025

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5 min read

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Angela Justice

Art collage, hand with coins on blue background. Concept of business and finance.

Antibody-drug conjugate (ADC)

Roche Ups ADC Bet With $1B in Biobucks for Oxford BioTherapeutics

Roche’s up to $1 billion investment will provide access to Oxford BioTherapeutics’ antibody-drug conjugate platform for undisclosed cancer targets.

March 19, 2025

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1 min read

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Tristan Manalac

Budget cuts, costs and unplanned expenses. Stress and nervousness. The concept of austerity and extortion. Inflation threatens savings. Poor financial planning. Reducing income. Expenses cover income.

Policy

Trump Eyes Steep Cuts to CDC HIV Prevention Program

The CDC budget cuts could pose headwinds for HIV drugmakers like Gilead and Merck but are unlikely to severely cripple their HIV divisions, according to analysts.

March 19, 2025

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2 min read

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Tristan Manalac

Dorval, Quebec, Canada - September 3, 2021: Novartis Pharmaceuticals Canada Inc. head office building in Dorval, Quebec, Canada. Novartis is a global healthcare company based in Switzerland.

Spinal muscular atrophy

Novartis’ Intrathecal Zolgensma Effective in Older Children

After bringing Zolgensma to market in 2019 as the first gene therapy for spinal muscular atrophy, Novartis is back with an intrathecal formulation intended for older patients.

March 19, 2025

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6 min read

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Heather McKenzie

Group Of Employees Being Fired By Their Company.

Layoffs

Cargo Lays Off 90% of Staff and Stops Development Work

The biotech is exploring opportunities for a reverse merger or other business combinations. CFO and now interim CEO Anup Radhakrishnan will take charge of these negotiations.

March 19, 2025

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2 min read

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Tristan Manalac

Podcasts

Sarepta’s Elevidys Death, FDA’s Vaccine Move, Weldon Whiplash, PDUFAs in Cardio

Sarepta will update Elevidys’ label after a patient died following treatment; the FDA issues flu vaccine recommendations without advisor input; Trump CDC nominee Dave Weldon pulled at last minute; and FDA decisions expected for Alnylam’s Amvuttra in ATTR-CM and Milestone’s etripamil in tachycardia.

March 19, 2025

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2 min read

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Heather McKenzie