BioSpace News Archive

Drug Development

Endemic COVID-19 Needs Novel, Prognostic Tests to Predict Severity and Progression

Some diagnostic developers are looking ahead to the time when COVID-19 is endemic throughout the population and most people are vaccinated. From a public health perspective, COVID-19 will be treated like the seasonal flu.

March 12, 2021
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4 min read
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Gail Dutton
Deals

Longboard, Prometheus Hit the Market with Hopes of Raising Over $250 Million Combined

The two pharmaceutical companies are going public and anticipate raising more than $250 million to advance research and development programs and support their business initiatives.

March 12, 2021
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2 min read
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Alex Keown
Four Biotechs Bringing Home the Bacon for Cancer Therapies, Vaccines and MRSA

Investment dollars continue to flood the life sciences industry as new technologies and groundbreaking approaches tear down the dams that have previously hindered advancement.

March 12, 2021
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4 min read
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Kate Goodwin
Drug Development

FDA Action Alert: Karyopharm, FibroGen and Kiniksa

The second half of March is a busy month for the U.S. Food and Drug Administration (FDA), with quite a few PDUFA dates scheduled. Here’s a look at this week’s target action dates.

March 12, 2021
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3 min read
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Mark Terry
Business

AVEO Puts Fotivda to the Test with BMS’ Opdivo in Kidney Cancer

Today, AVEO Oncology announced it had inked a clinical trial collaboration and supply deal with Bristol Myers Squibb to study Fotivda in combination with BMS’s checkpoint inhibitor Opdivo in advanced r/r RCC after previous immunotherapy exposure.

March 12, 2021
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2 min read
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Mark Terry
Drug Development

COVID-19 Vaccine News: Novavax Effective Against Variants; Sanofi/Translate Begin Early Trials

While existing vaccines are being rolled out worldwide, Novavax’s is demonstrating effectiveness in late-stage trials and the partnership of Sanofi and Translate Bio is beginning early-stage trials for their mRNA vaccine.

March 12, 2021
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3 min read
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Mark Terry
Drug Development

EMA Launches Safety Review After Patient of Zynteglo Gene Therapy Trial Develops Blood Cancer

The European Medicines Agency has launched a safety review of bluebird bio’s thalassaemia drug Zynteglo, a conditionally licensed gene therapy in Europe.

March 12, 2021
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2 min read
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Brandon May
Job Trends

Some Countries Pause Dosing of AstraZeneca Vaccine Due to Clotting Concerns

This morning, the World Health Organization issued a statement that there is no reason to stop using the vaccine because, as of this time, “no causal link has been established.”

March 12, 2021
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2 min read
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Alex Keown
BioCapital

Clinical Catch-Up: March 8-12

It was another busy week for clinical trial announcements. Here’s a look including trials for COVID-19, migraine, Parkinson’s disease, Alzheimer’s, HIV and more.

March 12, 2021
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10 min read
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Mark Terry
Preclinical Data Boosts Case for Cell Source’s CD8+ Veto Cells in BMT

Recently published data from a mouse model of sickle cell disease (SCD) is bolstering the case for the safety of Cell Source’s CD8+ veto cells, currently in Phase I/II testing to improve peripheral blood stem cell transplantation in patients with hematological malignancies.

March 12, 2021
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2 min read
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Mark Zipkin