miRagen Therapeutics, Inc. announced new data from two Phase 1 clinical trials of MRG-110, miRagen’s microRNA-92 inhibitor, in which administration of MRG-110 was observed to increase angiogenesis, as demonstrated by increased perfusion and histological markers of neoangiogenesis, as well as reduce alpha-smooth muscle actin expression, which has been show to correlate with activation of myofibroblasts.
October 16, 2019
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