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 Company Profile

Guilford Pharmaceuticals Inc. 

6611 Tributary Street

Baltimore  Maryland  21224  U.S.A.
Phone: 410-631-6300 Fax: 410-631-6485

Guilford Pharmaceuticals Inc. is a strategically driven innovator of novel pharmaceutical and biopolymer-based products that are intended to offer new and better treatments for serious medical conditions like Parkinson's disease, cancer and diabetic peripheral neuropathy. The company has two innovative technology platforms, a PHARMACEUTICAL PLATFORM and a BIOPOLYMER PLATFORM that have already spawned one commercial product and over a half a dozen novel product candidates.

  • Pharmaceutical Platform
    Guilford is using its expertise in neurobiology to discover and develop novel treatments for acute and chronic neurodegenerative disorders like Parkinson's disease, peripheral neuropathy and stroke. The Company currently has five distinct programs including its neuroimmunophilin, NAALADase, PARP and serine racemase inhibitor programs and a novel anesthetic agent called AQUAVANTM Injection.

  • Biopolymer Platform
    Guilford's biopolymer platform is designed to commercialize novel biopolymer-based products capable of delivering proven medicines in more effective ways--to increase efficacy and minimize harmful side effects. To date, this platform includes one product, GLIADEL® Wafer, and two product candidates, PACLIMER® Microspheres and LIDOMERTM Microspheres.

Business Strategy
Deploying its expertise in pharmaceutical and biopolymer discovery and development, Guilford's goal is to build a diversified biopharmaceutical company that is one of the most productive in its industry. To meet this goal, Guilford focuses on providing innovative solutions for large, under-serviced markets; diversifying drug development to manage risk and create opportunity; and implementing 'best industry practices' to accelerate its drug development efforts. The Company has an extensive patent portfolio that includes rights to over 100 U.S. patents and patent applications and over 700 foreign patents and patent applications.

Corporate Partnerships
Orion-Pharmos - Exclusive Scandinavian marketing, supply, and distribution agreement for GLIADEL® Wafer.
Daiichi Radioisotope Laboratories - Exclusive marketing, sales, and distribution rights to DOPASCAN® Injection for Japan, Korea, and Taiwan.

An Aggressive Agenda for 2001
In 2001 we’ve established an aggressive agenda for ourselves and hope to:
  • Submit a supplemental New Drug Application to seek approval to expand the market for GLIADEL® Wafer.
  • Complete a Phase I/II dose escalation study of PACLIMER® Microspheres in women with advanced ovarian cancer.
  • Commence additional studies to test PACLIMER® Microspheres as a treatment for intratumoral therapy of non-small cell lung cancer.
  • Complete a Phase II clinical trial of NIL-A in Parkinson's patients.
  • Complete a Phase I study and initiate a Phase II clinical trial of GPI-5693 for the treatment of neuropathic pain associated with diabetic peripheral neuropathy.
  • Complete a phase I study and initiate a Phase II clinical trial of AQUAVAN™ Injection.
  • Select a lead compound in our PARP inhibitor program.

Analyst Coverage
Matt Geller, CIBC
Stefan Loren, Legg Mason
John Sonnier, Prudential Vector Securities
Brian Rye CFA, Raymond James
Andrew Gitkin, UBS Warburg

Last Updated 11-8-01

 Key Statistics

Ownership: Public

Web Site: Guilford Pharmaceuticals Inc.
Employees: 300
Symbol: GLFD



Daiichi Pharmaceutical Co., Ltd.  Exclusive marketing, sales, and distribution rights to DOPASCAN ® Injection for Japan, Korea, and Taiwan.

Orion-Pharmos  Exclusive Scandinavian marketing, supply, and distribution agreement for GLIADEL ® Wafer.

 Company News
Biotech's Financial Lifeline 4/10/2006 12:49:29 PM    More...
MGI Pharma Inc. (MOGN) Announces Expiration Of Tender Offer For Guilford Pharmaceuticals Inc. (GLFD) Notes Due 2008 11/29/2005 12:39:42 PM    More...
MGI Pharma Inc. (MOGN) Announces Commencement Of Tender Offer Gor Guilford Pharmaceuticals Inc. (GLFD) Notes Due 2008 10/20/2005 2:48:50 PM    More...
Guilford Pharmaceuticals Inc. (GLFD) To Host Webcast Outlining New Corporate Strategy 10/19/2005 5:13:13 PM    More...
Guilford Pharmaceuticals Inc. (GLFD) To Host Webcast Outlining New Corporate Strategy 10/19/2005 5:13:12 PM    More...
Guilford Pharmaceuticals Inc. (GLFD) Stockholders Vote To Approve MGI Pharma Inc. (MOGN) Merger 10/19/2005 5:13:08 PM    More...
Guilford Pharmaceuticals Inc. (GLFD) Announces Phase III AQUAVAN(R) Trial Meets Primary Endpoint But Dosage Will Be Lowered 10/19/2005 5:13:07 PM    More...
Guilford Pharmaceuticals Inc. (GLFD) Release: AGGRASTAT(R) Injection Clinical Data Presented At American College Of Cardiology Annual Meeting 10/19/2005 5:12:57 PM    More...
Guilford Pharmaceuticals Inc. (GLFD) Reports 2004 Year-End Financial Results 10/19/2005 5:12:53 PM    More...
Guilford Pharmaceuticals Inc. (GLFD) To Announce 2004 Year-End Financial Results On Tuesday, March 1, 2005 10/19/2005 5:12:52 PM    More...