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Panacos Pharmaceuticals Inc. 

209 Perry Parkway
Suite 7
Gaithersburg  Maryland  20877  U.S.A.
Phone: 240-631-1395 Fax: 301-208-8755


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Panacos Pharmaceuticals Inc. is developing the next generation of anti-infective products through discovery and development of small molecule oral drugs for the treatment of HIV and other major human viral diseases. HIV infects approximately 1.7 million people in North America and Western Europe and approximately 40 million people worldwide. Approximately 650,000 patients are treated annually for HIV in the United States and Western Europe. Resistance to currently available drugs is one of the most pressing problems in HIV therapy and the leading cause of treatment failure. Panacos' proprietary discovery technologies are designed to combat resistance by focusing on novel targets in the virus life cycle, including virus maturation and virus fusion.

Panacos' lead candidate, bevirimat (PA-457), is the first in a new class of oral HIV therapeutics under development called maturation inhibitors, discovered by Panacos scientists and their academic collaborators. Based on its novel mechanism of action, bevirimat is designed to have potent activity against a broad range of HIV, including strains that are resistant to existing classes of drugs. The Company has completed seven clinical studies of bevirimat in over 300 subjects, showing significant reductions in viral load in HIV-infected subjects and a promising safety profile, and is currently in Phase 2b clinical trials.

The US Food and Drug Administration (FDA) has granted Fast Track designation to bevirimat. Fast Track is a process designed to expedite development and approval of new drugs that may have the potential to improve treatment for serious or life-threatening diseases. Developers of Fast Tracked products have greater access to FDA resources as well as eligibility for rolling NDA submissions. In addition, Fast Track designation may enable priority FDA review and accelerated approval.

In addition to bevirimat, Panacos is developing second generation maturation inhibitors and small molecule inhibitors of HIV fusion.

Last Updated: 11-17-2006

Key Statistics


Email:
Ownership: Public

Web Site: Panacos Pharmaceuticals Inc.
Employees: 40
Symbol: PANC
 



Industry
Pharmaceutical






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