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Tristan Manalac

Tristan Manalac

Senior Staff Writer

Tristan is BioSpace‘s senior staff writer. Based in Metro Manila, Tristan has more than eight years of experience writing about medicine, biotech and science. Being formally trained in molecular biology, he once dreamed of collecting degrees and starting his own lab. But these days, he finds his greatest joy in a bottle of beer and a beautiful sentence. He can be reached at tristan.manalac@biospace.com, tristan@tristanmanalac.com or on LinkedIn.

Elderly man examined by an ophthalmologist
Policy
Aldeyra Scores Late-Stage Clinical Win in Competitive Dry Eye Space
Aldeyra Therapeutics announced results from a crossover clinical trial, showing that its drug candidate reproxalap was effective in improving ocular redness and tear production in patients with dry eye disease.
July 12, 2022
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3 min read
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Tristan Manalac
Biotech Bay
CRISPR Pioneer Goes Small to Transform Genetic Medicine with Epigenetic Engineering
Epic Bio aims to transform genetic medicine by developing a new class of drugs that target the epigenome to alter gene expression.
July 12, 2022
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3 min read
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Tristan Manalac
Deals
Innoviva Snags Lucrative La Jolla Portfolio in $149M Deal
Innoviva Inc. and La Jolla Pharmaceutical Company announced Monday that they had entered into a $149-million merger agreement.
July 11, 2022
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3 min read
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Tristan Manalac
Drug Development
Long COVID Evidence Begins to Mount, Suggesting Biomarkers and a “Triangle” Effect
Scientists found that SARS-CoV-2 spike protein in the plasma could be a hallmark of long COVID, suggesting that the virus can linger in the body who suffer from prolonged symptoms.
July 11, 2022
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4 min read
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Tristan Manalac
Pascal Bachelet/BSIP/Universal Images Group via Ge
Drug Development
Adverum Slashes Workforce By 38%, Hones In On Eye Disease Candidate
Adverum Biotechnologies is cutting 78 jobs after announcing it had successfully amended its Investigational New Drug application for ADVM-022.to treat wet age-related macular degeneration.
July 8, 2022
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2 min read
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Tristan Manalac
Senior Female Scientist Works with High Tech Equipment in a Modern Laboratory. Her Colleagues are Working Beside Her.
Drug Development
Portage Adds Four Adenosine Candidates to Pipeline in Tarus Buyout
Portage Biotech announced Wednesday that it has inked an acquisition agreement with New York-based Tarus Therapeutics, adding four new candidates to its pipeline.
July 7, 2022
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3 min read
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Tristan Manalac
Drug Development
Applied Molecular Transport’s UC Candidate Proves Effective in Early-Stage Intervention
In patients stricken with ulcerative colitis for less than five years, AMT-101 was nearly three times more effective in inducing clinical remission than the placebo after eight weeks.
July 6, 2022
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3 min read
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Tristan Manalac
Pictured: Chinese flags in a row/iStock
Biopharma Investment in China is Thriving Amid U.S. Downturn
Many healthcare, pharmaceutical and biotech companies continue to place their bets on China, bringing fresh rounds of investments to and forging new partnerships with local firms.
July 5, 2022
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3 min read
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Tristan Manalac
Researchers Stumble Upon Potential Key to Slow DMD
Research scientists have found that a colony-stimulating factor 1 receptor inhibitor may also be a potential treatment for Duchenne muscular dystrophy.
July 5, 2022
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2 min read
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Tristan Manalac
Amarin, Secura Bio Face Disappointing Data, FDA Warning
Amarin released disappointing post hoc data from a sub-study of the REDUCE-IT trial, showing that its fish oil-derived Vascepa had little impact on serum biomarkers.
July 1, 2022
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3 min read
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Tristan Manalac
Aleksander Kalka/NurPhoto via Getty Images
Lone Star Bio
FUJIFILM Continues Cell Culture Quest, Invests $1.6B in Texas, Denmark Facilities
The $1.6-billion infusion into its subsidiary is Fujifilm’s latest move to establish a more robust presence in the cell culture manufacturing space.
June 30, 2022
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3 min read
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Tristan Manalac
Multiracial medical scientists in hazmat suit working with microscope and laptop computer inside modern laboratory hospital - Focus african man face
Drug Development
BeiGene, Lexicon and 9 Meters Wrap First Half with Clinical Wins
Capping off the first half of the year is a flurry of clinical trial wins. BioSpace takes a look at some of the most exciting ones:
June 30, 2022
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4 min read
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Tristan Manalac
Policy
FDA Advisory Committee Calls For Updated COVID-19 Boosters to Quell Omicron
Voting 19-2, the Vaccines and Related Biological Products Advisory Committee favored redesigning booster shots to include the coronavirus’ Omicron variant.
June 29, 2022
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2 min read
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Tristan Manalac
Drug Development
Eiger’s HDV Program Sees Cirrhosis in Younger Patients (Updated)
The findings, presented during a poster session at the EASL 2022 International Liver Congress, revealed that of the 407 D-LIVR participants, nearly 30% developed liver cirrhosis.
June 28, 2022
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3 min read
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Tristan Manalac
Business
Ascletis, Takeda, Arrowhead & More Present New Findings at EASL Liver Conference
For the first time in two years, the European Association for the Study of the Liver’s International Liver Congress was back on-site with cutting-edge research in hepatology and other sectors.
June 27, 2022
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5 min read
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Tristan Manalac
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