Advancing AAV Vector Production with High-Integrity DNA Constructs

ABOUT THE EVENT

Date: Tuesday, November 18, 2025 11–11:45am EST
Event Location: Virtual

Efficient and reproducible AAV vector production critically depends on the quality and integrity of the DNA constructs used during transfection.
PlasmidFactory provides a complete DNA solution portfolio — from classical plasmids to next-generation Minicircle DNA — enabling cleaner, safer, and more efficient AAV manufacturing across all development stages.

This webinar will highlight:

  • The 2-plasmid system as a validated, cost-effective alternative to conventional 3-plasmid setups, reducing complexity while maintaining performance.

  • The role of ITR integrity in achieving high vector yields and purity, and how ITRPROTECT® / ITRRESCUE® technologies safeguard full-length wt ITRs.

  • The scientific and process benefits of Minicircle DNA, a bacterial backbone-free format that improves AAV genome yield, purity, and transduction efficiency

Participants will learn how PlasmidFactory, as a trusted European CDMO, supports all modalities — amplification of customer plasmid systems, high-integrity plasmids, and innovative Minicircles — providing flexibility today and readiness for the regulatory standards of tomorrow.

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