C4 Therapeutics
About C4 Therapeutics
C4 Therapeutics is a private biotechnology company developing a new class of drugs based on Targeted Protein Degradation (TPD) to address a broad range of life-threatening and life-impairing diseases. C4T’s Degronimid™ platform uses small molecule drugs to direct the machinery of the ubiquitin-proteasome system to selectively degrade disease-relevant proteins for therapeutic benefit. Leveraging this distinctive mechanism provides new opportunities to target traditionally difficult to treat diseases and drug resistance. The wide-ranging potential of the Degronimid approach underpins C4T’s internal drug discovery programs as well as strategic partnerships with leading global pharmaceutical and biotechnology firms.
YEAR FOUNDED:
2015
LEADERSHIP:
Founder and CEO: Marc Cohen
Founders: Ken Anderson, Marc Cohen, Jay Bradner and Nathanael Gray
CSO: Andy Phillips
CAO: Andrea Armstrong
CBO: Tom Needham
JOBS:
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101 articles about C4 Therapeutics
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C4 Therapeutics Announces First Patient Dosed in Phase 1/2 Clinical Trial Evaluating CFT1946, an Orally Bioavailable BiDAC™ Degrader, in BRAF V600 Mutant Solid Tumors
1/30/2023
C4 Therapeutics, Inc. today announced that the first patient has been dosed in its Phase 1/2 clinical trial of CFT1946, an orally bioavailable mutant-selective BiDAC™ degrader for the treatment of BRAF V600 mutant solid tumors.
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C4 Therapeutics Announces 2023 Strategic Priorities to Advance Portfolio of Targeted Protein Degradation Medicines
1/9/2023
C4 Therapeutics, Inc. announced 2023 strategic priorities to advance its portfolio of targeted protein degradation medicines.
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C4 Therapeutics to Present at the 41st Annual J.P. Morgan Healthcare Conference
1/3/2023
C4 Therapeutics, Inc. announced that the Company will present at the upcoming 41st Annual J.P. Morgan Healthcare Conference in San Francisco on Monday, January 9th at 10:30 am PST.
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C4 Therapeutics Reports Third Quarter 2022 Financial Results and Recent Business Highlights
11/3/2022
C4 Therapeutics, Inc. reported financial results for the third quarter ended September 30, 2022, as well as recent business highlights.
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The FDA had a busy week, approving drugs, greenlighting clinical trials and other regulatory activities for Immuneering, Amylyx, Sarepta, Sanofi, and Regeneron and more.
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C4 Therapeutics Receives Study May Proceed Letter from U.S. FDA to Initiate Phase 1/2 Clinical Trial of CFT1946, an Orally Bioavailable BiDAC™ Degrader, in BRAF-V600 Mutant Solid Cancers
9/29/2022
C4 Therapeutics, Inc. today announced it has received a Study May Proceed Letter from the United States Food and Drug Administration (FDA) to begin a Phase 1/2 trial for CFT1946, an orally bioavailable mutant-selective BiDAC™ degrader for the treatment of BRAF-V600 mutant solid tumors.
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C4 Therapeutics Reports Second Quarter 2022 Financial Results and Recent Business Highlights
8/4/2022
C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedicated to advancing targeted protein degradation science to develop a new generation of small-molecule medicines and transform how disease is treated, today reported financial results for the second quarter ended June 30, 2022, as well as recent business highlights.
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C4 Therapeutics Appoints Experienced Clinical Development Leaders Laura Bessen, M.D. and Donna Grogan, M.D. to Board of Directors
8/2/2022
C4 Therapeutics, Inc. today announced the appointments of Laura Bessen, M.D. and Donna Grogan, M.D. to its board of directors.
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Closing out the month of May, plenty of companies presented or announced clinical trial updates and news. Here’s a look.
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C4 Therapeutics Announces First Patient Dosed in Phase 1/2 Clinical Trial Evaluating CFT8634, an Orally Bioavailable BiDAC™ Degrader for the Treatment of Synovial Sarcoma and SMARCB1-null Tumors
5/16/2022
C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), today announced that the first patient has been dosed in its Phase 1/2 clinical trial of CFT8634, an orally bioavailable BiDAC™ degrader targeting BRD9 for the treatment of SMARCB1-perturbed cancers, including synovial sarcoma and SMARCB1-null tumors.
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C4 Therapeutics Reports First Quarter 2022 Financial Results and Recent Business Highlights
5/5/2022
C4 Therapeutics, Inc. reported financial results for the first quarter ended March 31, 2022, as well as recent business highlights.
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Shares fell in several life sciences companies at the close of the market Friday on apparently lackluster early data from their respective research projects. We look into each one below:
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C4 Therapeutics Appoints Utpal Koppikar to Board of Directors
3/16/2022
C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company dedicated to advancing targeted protein degradation science to develop a new generation of small-molecule medicines and transform how disease is treated, announced the appointment of Utpal Koppikar, MBA, to its board of directors.
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C4 Therapeutics Announces FDA Orphan Drug Designation for CFT8634 for the Treatment of Soft Tissue Sarcoma
3/9/2022
C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedicated to advancing targeted protein degradation science to develop a new generation of small-molecule medicines and transform how disease is treated, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation (ODD) to CFT8634 for the treatment of soft tissue sarcoma.
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C4 Therapeutics to Present at the American Association for Cancer Research (AACR) Annual Meeting 2022
3/8/2022
C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedicated to advancing targeted protein degradation science to develop a new generation of small-molecule medicines and transform how disease is treated, today announced that the Company will present a poster and three oral presentations at the American Association for Cancer Research (AACR) Annual Meeting 2022.
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C4 Therapeutics Reports Full Year 2021 Financial Results and Recent Business Highlights
2/24/2022
C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC), a clinical-stage biopharmaceutical company dedicated to advancing targeted protein degradation science to develop a new generation of small-molecule medicines and transform how disease is treated, today reported business highlights and financial results for the year ended December 31, 2021.
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C4 Therapeutics Announces 2022 Key Milestones to Advance Targeted Protein Degradation Portfolio
1/10/2022
C4 Therapeutics, Inc. announced strategic priorities and 2022 milestones to advance its targeted protein degradation portfolio.
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C4 Therapeutics to Present at the 40th Annual J.P. Morgan Healthcare Conference
1/3/2022
C4 Therapeutics, Inc. today announced that the Company will present at the 40th Annual J.P. Morgan Healthcare Conference on Monday, January 10, 2022 at 10:30 a.m. EST.
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C4 Therapeutics Added to NASDAQ Biotechnology Index
12/17/2021
C4 Therapeutics, Inc. today announced its inclusion on the NASDAQ Biotechnology Index (Nasdaq: NBI), effective on December 20, 2021.
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Avilar Therapeutics officially joined the game with $60 million in seed financing from RA Capital Management.