BioSpace News Archive

New Results from Phase 1b/2 CARTITUDE-1 Study of BCMA-directed CAR-T Cell Therapy Cilta-cel in Treatment of Patients with RRMM to be Featured in Oral Presentation

ADC Therapeutics to Host Third Quarter 2020 Financial Results Conference Call on November 12, 2020

Nov. 5, 2020 12:15 UTC Acceleron Announces Third Quarter 2020 REBLOZYL ® Net Sales - Acceleron expects to report approximately $19.3 million in royalty revenue for Q3 2020 from approximately $96 million in net sales of REBLOZYL ® (luspatercept-aamt) as reported by Bristol Myers Squibb - - Acceleron will report its full third quarter 2020 financial and operating results after the close of U.S. financial markets today, November 5, 2020,

- Data from Phase 1 Trial with ADP-A2AFP in liver cancer presented at ILC confirm safety profile and demonstrate potential benefit for patients - - Safety and response data from dose escalation cohorts of the SURPASS trial to be presented at SITC - - Durability of response data from patients with synovial sarcoma from the Phase 1 ADP-A2M4 trial to be presented at CTOS - - Virtual Investor Day planned for November 20, 2020 - - Financial guidance confirmed: funded into 2022 -

Harpoon Therapeutics, Inc. (NASDAQ: HARP), a clinical-stage immunotherapy company developing novel T cell engagers, announced today that the preclinical data on HPN601 for the treatment of solid tumors has been accepted for oral presentation at the 35 th Society for Immunotherapy of Cancer (SITC) annual meeting. The virtual meeting takes place November 9-14, 2020. HPN601 targets the tumor antigen EpCAM and is based on Harpoon’s pr

– Preliminary data from first-in-human trial of menin inhibitor KO-539 accepted for oral presentation at ASH – – Encouraging safety, tolerability and activity with KO-539 highlighted in ASH abstract – – Preclinical data support expansion opportunity for tipifarnib plus PI3Kα inhibitor in HRAS- and/or PI3K-dependent tumors – – $325.4 million in cash, cash equivalents and investments provide runway into 2023 – – Management to host webcast and conference call today at 8:00 a.m. ET –

Phase 3 DISSOLVE clinical program with Sobi ongoing to evaluate SEL-212; topline data expected in the second half of 2022 IND filing for gene therapy expected in Q1 2021; preliminary Phase 1 data expected by end of 2021 IgA nephropathy program underway with IND expected by end of 2021 Ended quarter with cash position of $147.6 million with runway into the first quarter of 2023 Company to host conference call today at 8:30 a.m. ET

- Successful Financings, including $268 Million Initial Public Offering and $116 Million Series B Expected to Fund Through Proof of Concept Data in Co-lead Programs, Myotonic Dystrophy Type 1 and Duchenne Muscular Dystrophy -

Secured a development funding agreement related to elamipretide Phase 2b dry AMD study enrollment completion targeted by year-end Barth NDA preparation underway SBT-272 shows promise in additional neurological disease preclinical models Management to host conference call today at 8:30am ET

AVITA Therapeutics, Inc. (NASDAQ: RCEL, ASX:AVH), a regenerative medicine company that is developing and commercializing a technology platform that enables point-of-care autologous skin restoration for multiple unmet needs, announces today a correction in the time for the adjourned 2020 Annual Stockholder Meeting (“Adjourned Annual Meeting”), due to the change in daylight savings time Pacific Time in the United States