BioSpace News Archive

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Earnings

Pfizer CEO in Touch With President Over Most Favored Nation Drug Pricing

Albert Bourla confirmed that he called President Donald Trump after receiving a letter asking Pfizer and a clutch of other pharmaceutical companies to lower drug prices or face consequences.

August 5, 2025

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3 min read

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Annalee Armstrong

cartoon showing teamwork to build a bridge across a chasm

Gene therapy

Cracking the Commercial Code for Cell and Gene Therapies

From innovation in manufacturing to more-flexible regulation and better communication with payers, much needs to happen to make CGTs commercially viable. But it is possible, experts agreed at a recent panel.

August 5, 2025

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9 min read

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Jef Akst

Opinion

Fixing CGT Manufacturing Requires Not Automation, but a Return to Basics

The primary focus in scaling up production should first be the adoption of lean manufacturing principles used in virtually every other industry.

August 5, 2025

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5 min read

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Josh Ludwig

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Job Trends

July Layoffs Skyrocket 487% YOY With Merck Cuts

The number of biopharma professionals let go has increased year over year for three straight months. In July, as many as 8,000 people lost or were projected to lose their jobs, due largely to news that Merck projects to cut roughly 6,000 employees as part of a multiyear process.

August 5, 2025

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4 min read

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Angela Gabriel

Start of negative growth trend. Worsening forecast. Cessation of rise inertia, not enough power energy. The risk of recession and sliding into a crisis

Regulatory

Report of Patient Deaths Sends Agios Shares Seesawing

While the deaths occurred in patients who had been treated with Agios’ anemia treatment Pyrukynd, the biotech insisted in an SEC filing midday Monday that the drug’s risk-benefit profile remains unchanged.

August 5, 2025

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2 min read

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Tristan Manalac

Neuroscience

Praxis’ Seizure Drug Demonstrates ‘Impressive’ Efficacy in Mid-Stage Trial

Praxis’ vormatrigine reduced seizures by 56.3%, an effect size that, according to analysts at Truist Securities, exceeds that of its closest competitors.

August 5, 2025

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2 min read

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Tristan Manalac

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Regulatory

Scientists Behind Trial of Replimune’s Tumor Destroyer Protest FDA’s Rejection

In an open letter, 22 experts who designed and ran Replimune’s Phase III IGNYTE trial answered the FDA’s issues, as outlined in the complete response letter for the melanoma candidate RP1.

August 5, 2025

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2 min read

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Tristan Manalac

Press Releases

Hemato Oncology Testing Market Size to Hit USD 15.72 Billion by 2034

August 5, 2025

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1 min read

Press Releases

Animal Genetics Market Size on Track for USD 12.11 Billion Valuation by 2034